Bayesian molecular clock dating of species divergences in the genomics era

Mario dos Reis; Philip C J Donoghue; Ziheng Yang

doi:10.1038/nrg.2015.8

Bayesian molecular clock dating of species divergences in the genomics era

Mario dos Reis, Philip C J Donoghue, Ziheng Yang

Research output: Contribution to journal › Article (Academic Journal) › peer-review

114 Citations (Scopus)

649 Downloads (Pure)

Abstract

Five decades have passed since the proposal of the molecular clock hypothesis,
which states that the rate of evolution at the molecular level is constant through time and among species. This hypothesis has become a powerful tool in evolutionary biology, making it possible to use molecular sequences to estimate the geological ages of species divergence events. With recent advances in Bayesian clock dating methodology and the explosive accumulation of genetic sequence data, molecular clock dating has found widespread applications, from tracking virus pandemics and studying the macroevolutionary process of speciation and extinction to estimating a timescale for life on Earth

Original language	English
Pages (from-to)	71-80
Number of pages	10
Journal	Nature Reviews Genetics
Volume	17
Issue number	2
Early online date	21 Dec 2015
DOIs	https://doi.org/10.1038/nrg.2015.8
Publication status	Published - Feb 2016

Keywords

Molecular evolution
Phylogenetics
Speciation
Statistical methods

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10.1038/nrg.2015.8

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1 Active
2 Finished

Improving Bayesian methods for estimating divergence times integrating genomic and trait data
Donoghue , P. C. J.
25/03/16 → 31/12/21
Project: Research
The origin of plants: genomes, rocks, and biochemical cycles./
Donoghue , P. C. J.
1/01/16 → 31/12/18
Project: Research
Bayesian Estimation of Species Divergence Times Integrating Both Fossil and Molecular Information
Donoghue , P. C. J.
18/05/12 → 18/05/15
Project: Research

Cite this

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title = "Bayesian molecular clock dating of species divergences in the genomics era",

abstract = "Five decades have passed since the proposal of the molecular clock hypothesis,which states that the rate of evolution at the molecular level is constant through time and among species. This hypothesis has become a powerful tool in evolutionary biology, making it possible to use molecular sequences to estimate the geological ages of species divergence events. With recent advances in Bayesian clock dating methodology and the explosive accumulation of genetic sequence data, molecular clock dating has found widespread applications, from tracking virus pandemics and studying the macroevolutionary process of speciation and extinction to estimating a timescale for life on Earth",

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AB - Five decades have passed since the proposal of the molecular clock hypothesis,which states that the rate of evolution at the molecular level is constant through time and among species. This hypothesis has become a powerful tool in evolutionary biology, making it possible to use molecular sequences to estimate the geological ages of species divergence events. With recent advances in Bayesian clock dating methodology and the explosive accumulation of genetic sequence data, molecular clock dating has found widespread applications, from tracking virus pandemics and studying the macroevolutionary process of speciation and extinction to estimating a timescale for life on Earth

KW - Molecular evolution

KW - Phylogenetics

KW - Speciation

KW - Statistical methods

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DO - 10.1038/nrg.2015.8

M3 - Article (Academic Journal)

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ER -

Bayesian molecular clock dating of species divergences in the genomics era

Abstract

Keywords

Access to Document

Improving Bayesian methods for estimating divergence times integrating genomic and trait data

The origin of plants: genomes, rocks, and biochemical cycles./

Bayesian Estimation of Species Divergence Times Integrating Both Fossil and Molecular Information

Cite this