Bench Testing Analysis of Perforation Management in the Setting of Bifurcation Coronary Intervention

Rayyan Hemetsberger*, Anass Maaroufi, Kevin Hamzaraj, Judit Andreka, Mohammad Abdelghani, Serdar Farhan, Daniel Lootz, Johannes Gollmer, Nader Mankerious, Christian Hengstenberg, Tom W. Johnson, Gabor G. Toth

*Corresponding author for this work

Research output: Contribution to journalArticle (Academic Journal)peer-review

Abstract

Background:
Management of coronary perforation in bifurcation lesions with covered stents remains challenging.

Aims:
We aimed to describe a proper practice and toolbox for “jailed-branch” management after covered stent deployment.

Methods:
Using a bench model, we tested various wires with a 120° angulated microcatheter for their ability to penetrate covered stents to access jailed side branches (SB). Next, four PCI techniques were assessed: Test #1 (main branch [MB] rupture simulation): MB covered stent, graft penetration, and kissing balloon inflation (KBI) (n = 7). Test #2: Test #1 completed with Culotte using a drug-eluting stent (DES) (n = 3). Test #3: Culotte with two covered stents simulating MB and SB rupture (n = 3). Test #4: Test #3 plus final DES in MB (n = 3).

Results:
High tip-load wires ( > 12 g) successfully penetrated covered stents within 14 s. All procedures were completed successfully. Test #1 showed lumen area reductions of –8% (MB) and –25% (SB), with graft overhang at the SB. Conversion to Culotte with DES (Test #2) improved SB lumen reduction to –8%. Test #3 showed reductions of –7% (MB) and –15% (SB), with graft overhang at MB, corrected in Test #4 by DES implantation, resulting in +9% lumen gain (MB) and improved SB lumen reduction (–11%).

Conclusion:
In this bifurcation perforation in-bench model, high tip-load wires effectively penetrated covered stents toward excluded branches after crossover covered stent implantation. Conversion to Culotte, using either a DES or a second covered stent, was feasible. Overhanging graft material following SB fenestration could be addressed by overstenting with a DES.
Original languageEnglish
Number of pages10
JournalCatheterization and Cardiovascular Interventions
Early online date12 Dec 2025
DOIs
Publication statusE-pub ahead of print - 12 Dec 2025

Bibliographical note

Publisher Copyright:
© 2025 The Author(s). Catheterization and Cardiovascular Interventions published by Wiley Periodicals LLC.

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