Beta2-adrenoceptor polymorphisms and asthma from childhood to middle age in the British 1958 birth cohort: a genetic association study

Ian P Hall, John D Blakey, Khalid A Al Balushi, Amanda Wheatley, Ian Sayers, Marcus E Pembrey, Susan M Ring, Wendy L McArdle, David P Strachan

Research output: Contribution to journalArticle (Academic Journal)

88 Citations (Scopus)

Abstract

Functionally relevant polymorphisms of the beta2-adrenoceptor gene (ADRB2) are common in white populations, but their contribution to the burden of airways disease in the population is uncertain. We aimed to relate the long-term prevalence of asthma or wheeze to functional coding region polymorphisms in the ADRB2 gene.
Original languageEnglish
Pages (from-to)771-9
Number of pages9
JournalLancet
Volume368
Issue number9537
DOIs
Publication statusPublished - 2006

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