Abstract
Morphologically complex amorphous calcium phosphate nanostructures are synthesized within supersaturated water-in-oil miniemulsions stabilized by a mixture of a calcium bis(2-ethylhexyl)phosphate (Ca(DEHP)2) surfactant and poly(ethylene oxide)19-poly(propylene oxide)69-poly(ethylene oxide)19 (P123) triblock copolymer. Solvent evaporation at room temperature results in self-supporting viscous organogels comprising an interconnected network of calcium phosphate nanofilaments embedded within a continuous polymer/surfactant matrix. The P123/DEHP/calcium phosphate organogels are employed as a bioactive filler for the occlusion of exposed dentine tubules using a standard bovine tooth model.
Original language | English |
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Pages (from-to) | 5965-5972 |
Number of pages | 8 |
Journal | Chemistry of Materials |
Volume | 26 |
Issue number | 20 |
DOIs | |
Publication status | Published - 28 Oct 2014 |
Research Groups and Themes
- Bristol BioDesign Institute
Keywords
- synthetic biology
- HYDROPHILIC BLOCK-COPOLYMERS
- AMORPHOUS CALCIUM-PHOSPHATE
- MINERALIZATION
- NANOPARTICLES
- MICROEMULSIONS
- CRYSTALLIZATION
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Dive into the research topics of 'Bioactive hybrid organogels based on miniemulsion synthesis of morphologically complex polymer/surfactant/calcium phosphate nanostructures'. Together they form a unique fingerprint.Profiles
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Dr Sean A Davis
- School of Chemistry - Senior Lecturer
- Soft Matter, Colloids and Materials
Person: Academic , Member