Biomedical applications of metal organic polygons and polyhedra (MOPs)

Soumen K. Samanta*, Lyle Isaacs*

*Corresponding author for this work

Research output: Contribution to journalReview article (Academic Journal)peer-review

14 Citations (Scopus)


Since the discovery and structural characterization of metal organic polygons and polyhedra (MOPs), scientists have explored their potential in various applications like catalysis, separation, storage, and sensing. In recent years, scientists have explored the potential of supramolecular MOPs in biomedical application. Pioneering works by Ehrlich, Rosenberg, Lippard, Stang and others have demonstrated that MOPs have great potential as a novel class of metallo-therapeutics that can deliver cargoes (drugs and dyes) selectively. In this article, we document the progress made over the past two decades on the biomedical applications of MOPs and discuss the future prospects of this emerging field.

Original languageEnglish
Article number213181
JournalCoordination Chemistry Reviews
Early online date19 Feb 2020
Publication statusPublished - 15 May 2020


  • Antitumor agents
  • Drug delivery
  • Drug formulation
  • Metallotherapeutics
  • MOPs


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