TY - JOUR
T1 - Biomedical applications of metal organic polygons and polyhedra (MOPs)
AU - Samanta, Soumen K.
AU - Isaacs, Lyle
PY - 2020/5/15
Y1 - 2020/5/15
N2 - Since the discovery and structural characterization of metal organic polygons and polyhedra (MOPs), scientists have explored their potential in various applications like catalysis, separation, storage, and sensing. In recent years, scientists have explored the potential of supramolecular MOPs in biomedical application. Pioneering works by Ehrlich, Rosenberg, Lippard, Stang and others have demonstrated that MOPs have great potential as a novel class of metallo-therapeutics that can deliver cargoes (drugs and dyes) selectively. In this article, we document the progress made over the past two decades on the biomedical applications of MOPs and discuss the future prospects of this emerging field.
AB - Since the discovery and structural characterization of metal organic polygons and polyhedra (MOPs), scientists have explored their potential in various applications like catalysis, separation, storage, and sensing. In recent years, scientists have explored the potential of supramolecular MOPs in biomedical application. Pioneering works by Ehrlich, Rosenberg, Lippard, Stang and others have demonstrated that MOPs have great potential as a novel class of metallo-therapeutics that can deliver cargoes (drugs and dyes) selectively. In this article, we document the progress made over the past two decades on the biomedical applications of MOPs and discuss the future prospects of this emerging field.
KW - Antitumor agents
KW - Drug delivery
KW - Drug formulation
KW - Metallotherapeutics
KW - MOPs
UR - http://www.scopus.com/inward/record.url?scp=85079627070&partnerID=8YFLogxK
U2 - 10.1016/j.ccr.2020.213181
DO - 10.1016/j.ccr.2020.213181
M3 - Review article (Academic Journal)
C2 - 32255835
AN - SCOPUS:85079627070
SN - 0010-8545
VL - 410
JO - Coordination Chemistry Reviews
JF - Coordination Chemistry Reviews
M1 - 213181
ER -