Blood pressure regulation in humans: calculation of an "error signal" in control of sympathetic nerve activity

E A Wehrwein; M J Joyner; ECJ Hart; B G Wallin; T Karlsson; N Charkoudian

doi:10.1161/​HYPERTENSIONAHA.109.141739

Blood pressure regulation in humans: calculation of an "error signal" in control of sympathetic nerve activity

E A Wehrwein, M J Joyner, ECJ Hart, B G Wallin, T Karlsson, N Charkoudian

School of Physiology, Pharmacology & Neuroscience

Research output: Contribution to journal › Article (Academic Journal) › peer-review

30 Citations (Scopus)

Abstract

Within an individual, diastolic blood pressure (DBP) is negatively related to sympathetic burst incidence, such that lower pressure is associated with high burst incidence. Our goal was to explore the use of a calculation of a DBP "error signal" in the control of muscle sympathetic nerve activity in men and women. Baseline muscle sympathetic nerve activity was measured in healthy young men (n=22) and women (n=28). Women had significantly lower muscle sympathetic nerve activity than men (29+/-3 versus 43+/-2 bursts per 100 heartbeats; P

Translated title of the contribution	Blood pressure regulation in humans: calculation of an "error signal" in control of sympathetic nerve activity
Original language	English
Pages (from-to)	264 - 269
Number of pages	6
Journal	Hypertension
Volume	55
DOIs	https://doi.org/10.1161/HYPERTENSIONAHA.109.141739
Publication status	Published - Feb 2010

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abstract = "Within an individual, diastolic blood pressure (DBP) is negatively related to sympathetic burst incidence, such that lower pressure is associated with high burst incidence. Our goal was to explore the use of a calculation of a DBP {"}error signal{"} in the control of muscle sympathetic nerve activity in men and women. Baseline muscle sympathetic nerve activity was measured in healthy young men (n=22) and women (n=28). Women had significantly lower muscle sympathetic nerve activity than men (29+/-3 versus 43+/-2 bursts per 100 heartbeats; P",

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T1 - Blood pressure regulation in humans: calculation of an "error signal" in control of sympathetic nerve activity

AU - Wehrwein, E A

AU - Joyner, M J

AU - Hart, ECJ

AU - Wallin, B G

AU - Karlsson, T

AU - Charkoudian, N

PY - 2010/2

Y1 - 2010/2

N2 - Within an individual, diastolic blood pressure (DBP) is negatively related to sympathetic burst incidence, such that lower pressure is associated with high burst incidence. Our goal was to explore the use of a calculation of a DBP "error signal" in the control of muscle sympathetic nerve activity in men and women. Baseline muscle sympathetic nerve activity was measured in healthy young men (n=22) and women (n=28). Women had significantly lower muscle sympathetic nerve activity than men (29+/-3 versus 43+/-2 bursts per 100 heartbeats; P

AB - Within an individual, diastolic blood pressure (DBP) is negatively related to sympathetic burst incidence, such that lower pressure is associated with high burst incidence. Our goal was to explore the use of a calculation of a DBP "error signal" in the control of muscle sympathetic nerve activity in men and women. Baseline muscle sympathetic nerve activity was measured in healthy young men (n=22) and women (n=28). Women had significantly lower muscle sympathetic nerve activity than men (29+/-3 versus 43+/-2 bursts per 100 heartbeats; P

U2 - 10.1161/HYPERTENSIONAHA.109.141739

DO - 10.1161/HYPERTENSIONAHA.109.141739

M3 - Article (Academic Journal)

SN - 1524-4563

VL - 55

SP - 264

EP - 269

JO - Hypertension

JF - Hypertension

ER -

Blood pressure regulation in humans: calculation of an "error signal" in control of sympathetic nerve activity

Abstract

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