Blood pressure regulation in humans: calculation of an "error signal" in control of sympathetic nerve activity

E A Wehrwein, M J Joyner, ECJ Hart, B G Wallin, T Karlsson, N Charkoudian

Research output: Contribution to journalArticle (Academic Journal)peer-review

20 Citations (Scopus)

Abstract

Within an individual, diastolic blood pressure (DBP) is negatively related to sympathetic burst incidence, such that lower pressure is associated with high burst incidence. Our goal was to explore the use of a calculation of a DBP "error signal" in the control of muscle sympathetic nerve activity in men and women. Baseline muscle sympathetic nerve activity was measured in healthy young men (n=22) and women (n=28). Women had significantly lower muscle sympathetic nerve activity than men (29+/-3 versus 43+/-2 bursts per 100 heartbeats; P
Translated title of the contributionBlood pressure regulation in humans: calculation of an "error signal" in control of sympathetic nerve activity
Original languageEnglish
Pages (from-to)264 - 269
Number of pages6
JournalHypertension
Volume55
DOIs
Publication statusPublished - Feb 2010

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