Abstract
8-Substituted tertiary 1-naphthamides are chiral, atropisomeric compounds at room temperature, and the rate at which they racemise (by rotation about the Ar-CO bond) depends principally on the extent to which the 8-substituent undergoes incipient nucleophilic addition to the amide carbonyl group, as indicated by X-ray crystallography.
Original language | English |
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Pages (from-to) | 2059-2060 |
Number of pages | 2 |
Journal | Chemical Communications |
Issue number | 20 |
DOIs | |
Publication status | Published - 21 Oct 1999 |