Boryl (Hetero)aryne Precursors as Versatile Arylation Reagents: Synthesis via C-H Activation and Orthogonal Reactivity

Emilien Demory, Karthik Devaraj, Andreas Orthaber, Paul Gates, Lukasz T. Pilarski

Research output: Contribution to journalArticle (Academic Journal)peer-review

45 Citations (Scopus)
275 Downloads (Pure)

Abstract

Pinacolato boronyl ortho-silyl(hetero)aryltriflates are presented as a new class of building block for arylation. They demonstrate unique versatility by delivering boronate or (hetero)aryne reactivity chemoselectively for a notably broad reaction scope. This marks the unprecedented postfunctionalization of fluoride-activated
(hetero)aryne precursors, including as substrates in transition metal catalysis, and it offers valuable new arylboronate postfunctionalizations without use of specialized protecting groups.
Original languageEnglish
Pages (from-to)11765-11769
Number of pages5
JournalAngewandte Chemie - International Edition
Volume54
Issue number40
DOIs
Publication statusPublished - 28 Sep 2015

Bibliographical note

Date of Acceptance: 14/07/2015

Fingerprint Dive into the research topics of 'Boryl (Hetero)aryne Precursors as Versatile Arylation Reagents: Synthesis via C-H Activation and Orthogonal Reactivity'. Together they form a unique fingerprint.

Cite this