Bottom-up assembly of viral replication cycles

Oskar Staufer*, Gösta Gantner, Ilia Platzman, Klaus Tanner, Imre Berger, Joachim P Spatz

*Corresponding author for this work

Research output: Contribution to journalReview article (Academic Journal)peer-review

3 Citations (Scopus)
28 Downloads (Pure)

Abstract

Bottom-up synthetic biology provides new means to understand living matter by constructing minimal life-like systems. This principle can also be applied to study infectious diseases. Here we summarize approaches and ethical considerations for the bottom-up assembly of viral replication cycles.

Original languageEnglish
Article number6530
JournalNature Communications
Volume13
Issue number1
DOIs
Publication statusPublished - 2 Nov 2022

Bibliographical note

Funding Information:
The authors acknowledge the support from the Max Planck School Matter to Life. J.P.S. is the Weston Visiting Professor at the Weizmann Institute of Science and part of the excellence cluster CellNetworks at the University of Heidelberg. O.S. acknowledges the support from the Joachim Herz Foundation. J.P.S. and I.P. acknowledge funding from the Federal Ministry of Education and Research of Germany, Grant Agreement no. 13XP5073A, PolyAntiBak and the MaxSynBio Consortium, which is jointly funded by the Federal Ministry of Education and Research of Germany and the Max Planck Society. J.P.S. acknowledges support through the promotion prize for German Scientists in the Gottfried Wilhelm Leibniz Program of the German Research Foundation (DFG)”. J.P.S also acknowledge the support from the SFB 1129 and the Excellence Cluster “3D Matter Made to Order” at Heidelberg University (EXC-2082/1-390761711) of the German Research Foundation (DFG). J.P.S. and I.P. also acknowledge the support from the Volkswagen Stiftung (priority call ‘Life?’). I.B. is an Investigator of the Wellcome Trust (106115/Z/14/Z) and acknowledges support by the European Research Council (AdvG 834631) and the Bristol Synthetic Biology Centre BrisSynBio. Parts of the drawings were created with BioRender.com. The generous support of the Max Planck Society is appreciated.

Funding Information:
The authors acknowledge the support from the Max Planck School Matter to Life. J.P.S. is the Weston Visiting Professor at the Weizmann Institute of Science and part of the excellence cluster CellNetworks at the University of Heidelberg. O.S. acknowledges the support from the Joachim Herz Foundation. J.P.S. and I.P. acknowledge funding from the Federal Ministry of Education and Research of Germany, Grant Agreement no. 13XP5073A, PolyAntiBak and the MaxSynBio Consortium, which is jointly funded by the Federal Ministry of Education and Research of Germany and the Max Planck Society. J.P.S. acknowledges support through the promotion prize for German Scientists in the Gottfried Wilhelm Leibniz Program of the German Research Foundation (DFG)”. J.P.S also acknowledge the support from the SFB 1129 and the Excellence Cluster “3D Matter Made to Order” at Heidelberg University (EXC-2082/1-390761711) of the German Research Foundation (DFG). J.P.S. and I.P. also acknowledge the support from the Volkswagen Stiftung (priority call ‘Life?’). I.B. is an Investigator of the Wellcome Trust (106115/Z/14/Z) and acknowledges support by the European Research Council (AdvG 834631) and the Bristol Synthetic Biology Centre BrisSynBio. Parts of the drawings were created with BioRender.com. The generous support of the Max Planck Society is appreciated.

Publisher Copyright:
© 2022, The Author(s).

Structured keywords

  • Bristol BioDesign Institute
  • Max Planck Bristol

Keywords

  • Synthetic Biology
  • Virus Replication

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