Branch-selective, iridium-catalyzed hydroarylation of monosubstituted alkenes via a cooperative destabilization strategy

Giacomo E M Crisenza; Niall McCreanor; John F. Bower

doi:10.1021/ja505776m

Branch-selective, iridium-catalyzed hydroarylation of monosubstituted alkenes via a cooperative destabilization strategy

Giacomo E M Crisenza
, Niall McCreanor
, John F. Bower^*

^*Corresponding author for this work

School of Chemistry

Research output: Contribution to journal › Article (Academic Journal) › peer-review

141 Citations (Scopus)

347 Downloads (Pure)

Abstract

Highly branch-selective, carbonyl-directed hydroarylations of monosubstituted alkenes are described. The chemistry relies upon a cationic Ir(I) catalyst modified with an electron deficient, wide bite angle bisphosphine ligand. This work provides a regioisomeric alternative to the Murai hydroarylation protocol.

Original language	English
Pages (from-to)	10258-10261
Number of pages	4
Journal	Journal of the American Chemical Society
Volume	136
Issue number	29
DOIs	https://doi.org/10.1021/ja505776m
Publication status	Published - 23 Jul 2014

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10.1021/ja505776m

ja505776mFinal published version, 1.32 MBLicence: CC BY

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@article{fda5a1f33b2645ee93563257b4b76b21,

title = "Branch-selective, iridium-catalyzed hydroarylation of monosubstituted alkenes via a cooperative destabilization strategy",

abstract = "Highly branch-selective, carbonyl-directed hydroarylations of monosubstituted alkenes are described. The chemistry relies upon a cationic Ir(I) catalyst modified with an electron deficient, wide bite angle bisphosphine ligand. This work provides a regioisomeric alternative to the Murai hydroarylation protocol.",

author = "Crisenza, \{Giacomo E M\} and Niall McCreanor and Bower, \{John F.\}",

year = "2014",

month = jul,

day = "23",

doi = "10.1021/ja505776m",

language = "English",

volume = "136",

pages = "10258--10261",

journal = "Journal of the American Chemical Society",

issn = "0002-7863",

publisher = "American Chemical Society",

number = "29",

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TY - JOUR

T1 - Branch-selective, iridium-catalyzed hydroarylation of monosubstituted alkenes via a cooperative destabilization strategy

AU - Crisenza, Giacomo E M

AU - McCreanor, Niall

AU - Bower, John F.

PY - 2014/7/23

Y1 - 2014/7/23

N2 - Highly branch-selective, carbonyl-directed hydroarylations of monosubstituted alkenes are described. The chemistry relies upon a cationic Ir(I) catalyst modified with an electron deficient, wide bite angle bisphosphine ligand. This work provides a regioisomeric alternative to the Murai hydroarylation protocol.

AB - Highly branch-selective, carbonyl-directed hydroarylations of monosubstituted alkenes are described. The chemistry relies upon a cationic Ir(I) catalyst modified with an electron deficient, wide bite angle bisphosphine ligand. This work provides a regioisomeric alternative to the Murai hydroarylation protocol.

UR - https://www.scopus.com/pages/publications/84904865660

U2 - 10.1021/ja505776m

DO - 10.1021/ja505776m

M3 - Article (Academic Journal)

C2 - 25019322

AN - SCOPUS:84904865660

SN - 0002-7863

VL - 136

SP - 10258

EP - 10261

JO - Journal of the American Chemical Society

JF - Journal of the American Chemical Society

IS - 29

ER -

Branch-selective, iridium-catalyzed hydroarylation of monosubstituted alkenes via a cooperative destabilization strategy

Abstract

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New enantioselective metal-catalysed C-N and C-C bond forming reactions

3-month Core Capability for Chemistry Research

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Branch-selective, iridium-catalyzed hydroarylation of monosubstituted alkenes via a cooperative destabilization strategy

Abstract

Research Groups and Themes

Access to Document

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New enantioselective metal-catalysed C-N and C-C bond forming reactions

3-month Core Capability for Chemistry Research

Cite this