Breaking the speed limit with atomic force microscopy

LM Picco, L Bozec, A Ulcinas, DJ Engledew, M Antognozzi, MA Horton, MJ Miles

Research output: Contribution to journalArticle (Academic Journal)peer-review

207 Citations (Scopus)


High-speed atomic force microscopy (AFM) is important for following processes that occur on sub-second timescales for studies both in biology and materials science, and also for the ability to examine large areas of a specimen at high resolution in a practical length of time. Further developments of the previously reported high-speed contact-mode AFM are described. Two instruments are presented: (i) a high-speed flexure stage arrangement capable of imaging at a video rate of 30 fps, and (ii) an ultra-high speed instrument using a combined tuning fork and flexure-stage scanning system capable of ultra-high-speed imaging in excess of 1000 fps. Results of imaging collagen fibres under ambient conditions at rates of up to 1300 frames s-1 are presented. Despite tip–specimen relative velocities of up to 200 mm s-1, no significant damage to the collagen specimen was observed even after tens of thousands of frames were acquired in the same area of the specimen.
Translated title of the contributionBreaking the speed limit with atomic force microscopy
Original languageEnglish
Pages (from-to)044030/1 - 044030/4
Number of pages4
Publication statusPublished - Jan 2007

Bibliographical note

Publisher: Institute of Physics Publishing


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