C-reactive protein is a useful predictor of metronidazole treatment failure in mild-to-moderate Clostridium difficile infection

Hugo A Farne; Natasha K Martin; Janice Main; Timothy Orchard; Jonathan Tyrrell-Price

doi:10.1097/MEG.0b013e328359ed6c

C-reactive protein is a useful predictor of metronidazole treatment failure in mild-to-moderate Clostridium difficile infection

Hugo A Farne, Natasha K Martin, Janice Main, Timothy Orchard, Jonathan Tyrrell-Price

Research output: Contribution to journal › Article (Academic Journal) › peer-review

6 Citations (Scopus)

Abstract

To assess the ability of C-reactive (CRP) protein, against the other commonly used metrics, to predict metronidazole treatment failure in Clostridium difficile infection.

Original language	English
Pages (from-to)	33-6
Number of pages	4
Journal	European Journal of Gastroenterology and Hepatology
Volume	25
Issue number	1
DOIs	https://doi.org/10.1097/MEG.0b013e328359ed6c
Publication status	Published - Jan 2013

Keywords

Severity of Illness Index
Metronidazole
Anti-Infective Agents
Treatment Failure
Odds Ratio
Humans
Retrospective Studies
Aged
Predictive Value of Tests
Leukocyte Count
C-Reactive Protein
Drug Substitution
Creatinine
Aged, 80 and over
Logistic Models
Vancomycin
Middle Aged
Clostridium difficile
Clostridium Infections
Time Factors
Male
Biological Markers
Female

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@article{eb86e2828ce949119ae53312c1d010f1,

title = "C-reactive protein is a useful predictor of metronidazole treatment failure in mild-to-moderate Clostridium difficile infection",

abstract = "To assess the ability of C-reactive (CRP) protein, against the other commonly used metrics, to predict metronidazole treatment failure in Clostridium difficile infection.",

keywords = "Severity of Illness Index, Metronidazole, Anti-Infective Agents, Treatment Failure, Odds Ratio, Humans, Retrospective Studies, Aged, Predictive Value of Tests, Leukocyte Count, C-Reactive Protein, Drug Substitution, Creatinine, Aged, 80 and over, Logistic Models, Vancomycin, Middle Aged, Clostridium difficile, Clostridium Infections, Time Factors, Male, Biological Markers, Female",

author = "Farne, {Hugo A} and Martin, {Natasha K} and Janice Main and Timothy Orchard and Jonathan Tyrrell-Price",

year = "2013",

month = jan,

doi = "10.1097/MEG.0b013e328359ed6c",

language = "English",

volume = "25",

pages = "33--6",

journal = "European Journal of Gastroenterology and Hepatology",

issn = "1473-5687",

publisher = "Lippincott Williams and Wilkins",

number = "1",

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TY - JOUR

T1 - C-reactive protein is a useful predictor of metronidazole treatment failure in mild-to-moderate Clostridium difficile infection

AU - Farne, Hugo A

AU - Martin, Natasha K

AU - Main, Janice

AU - Orchard, Timothy

AU - Tyrrell-Price, Jonathan

PY - 2013/1

Y1 - 2013/1

N2 - To assess the ability of C-reactive (CRP) protein, against the other commonly used metrics, to predict metronidazole treatment failure in Clostridium difficile infection.

AB - To assess the ability of C-reactive (CRP) protein, against the other commonly used metrics, to predict metronidazole treatment failure in Clostridium difficile infection.

KW - Severity of Illness Index

KW - Metronidazole

KW - Anti-Infective Agents

KW - Treatment Failure

KW - Odds Ratio

KW - Humans

KW - Retrospective Studies

KW - Aged

KW - Predictive Value of Tests

KW - Leukocyte Count

KW - C-Reactive Protein

KW - Drug Substitution

KW - Creatinine

KW - Aged, 80 and over

KW - Logistic Models

KW - Vancomycin

KW - Middle Aged

KW - Clostridium difficile

KW - Clostridium Infections

KW - Time Factors

KW - Male

KW - Biological Markers

KW - Female

U2 - 10.1097/MEG.0b013e328359ed6c

DO - 10.1097/MEG.0b013e328359ed6c

M3 - Article (Academic Journal)

C2 - 23026925

SN - 1473-5687

VL - 25

SP - 33

EP - 36

JO - European Journal of Gastroenterology and Hepatology

JF - European Journal of Gastroenterology and Hepatology

IS - 1

ER -

C-reactive protein is a useful predictor of metronidazole treatment failure in mild-to-moderate Clostridium difficile infection

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Keywords

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