C(5) Site-Selective Functionalization of (S)-Cotinine

Hugo Rego Campello, Timothy Gallagher*

*Corresponding author for this work

Research output: Contribution to journalArticle (Academic Journal)peer-review

227 Downloads (Pure)

Abstract

(S)-(-)-Cotinine 2 undergoes direct and site-selective iridium-catalyzed borylation to provide boronate ester 3 and bromide 4 which offer flexible entry to a range of C(5)-substituted cotinine variants.

Original languageEnglish
Pages (from-to)516-520
Number of pages5
JournalJournal of Organic Chemistry
Volume83
Issue number1
Early online date5 Dec 2017
DOIs
Publication statusPublished - 5 Jan 2018

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