Campylobacter jejuni gene expression in the chick cecum: evidence for adaptation to a low-oxygen environment

C A Woodall; M A Jones; P A Barrow; J Hinds; G L Marsden; D J Kelly; N Dorrell; B W Wren; D J Maskell

doi:10.1128/IAI.73.8.5278-5285.2005

Campylobacter jejuni gene expression in the chick cecum: evidence for adaptation to a low-oxygen environment

C A Woodall, M A Jones, P A Barrow, J Hinds, G L Marsden, D J Kelly, N Dorrell, B W Wren, D J Maskell

Research output: Contribution to journal › Article (Academic Journal) › peer-review

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Abstract

Transcriptional profiling of Campylobacter jejuni during colonization of the chick cecum identified 59 genes that were differentially expressed in vivo compared with the genes in vitro. The data suggest that C. jejuni regulates electron transport and central metabolic pathways to alter its physiological state during establishment in the chick cecum.

Original language	English
Pages (from-to)	5278-85
Number of pages	8
Journal	Infection and Immunity
Volume	73
Issue number	8
DOIs	https://doi.org/10.1128/IAI.73.8.5278-5285.2005
Publication status	Published - 10 Aug 2005

Keywords

Adaptation, Physiological
Animals
Campylobacter Infections/metabolism
Campylobacter jejuni/genetics
Cecum/microbiology
Chickens/microbiology
Electron Transport
Gene Expression/physiology
Gene Expression Profiling
Oligonucleotide Array Sequence Analysis
Oxygen/metabolism

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@article{7130577ff545462b95f873d9ac202fd8,

title = "Campylobacter jejuni gene expression in the chick cecum: evidence for adaptation to a low-oxygen environment",

abstract = "Transcriptional profiling of Campylobacter jejuni during colonization of the chick cecum identified 59 genes that were differentially expressed in vivo compared with the genes in vitro. The data suggest that C. jejuni regulates electron transport and central metabolic pathways to alter its physiological state during establishment in the chick cecum.",

keywords = "Adaptation, Physiological, Animals, Campylobacter Infections/metabolism, Campylobacter jejuni/genetics, Cecum/microbiology, Chickens/microbiology, Electron Transport, Gene Expression/physiology, Gene Expression Profiling, Oligonucleotide Array Sequence Analysis, Oxygen/metabolism",

author = "Woodall, {C A} and Jones, {M A} and Barrow, {P A} and J Hinds and Marsden, {G L} and Kelly, {D J} and N Dorrell and Wren, {B W} and Maskell, {D J}",

year = "2005",

month = aug,

day = "10",

doi = "10.1128/IAI.73.8.5278-5285.2005",

language = "English",

volume = "73",

pages = "5278--85",

journal = "Infection and Immunity",

issn = "0019-9567",

publisher = "American Society for Microbiology",

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TY - JOUR

T1 - Campylobacter jejuni gene expression in the chick cecum

T2 - evidence for adaptation to a low-oxygen environment

AU - Woodall, C A

AU - Jones, M A

AU - Barrow, P A

AU - Hinds, J

AU - Marsden, G L

AU - Kelly, D J

AU - Dorrell, N

AU - Wren, B W

AU - Maskell, D J

PY - 2005/8/10

Y1 - 2005/8/10

N2 - Transcriptional profiling of Campylobacter jejuni during colonization of the chick cecum identified 59 genes that were differentially expressed in vivo compared with the genes in vitro. The data suggest that C. jejuni regulates electron transport and central metabolic pathways to alter its physiological state during establishment in the chick cecum.

AB - Transcriptional profiling of Campylobacter jejuni during colonization of the chick cecum identified 59 genes that were differentially expressed in vivo compared with the genes in vitro. The data suggest that C. jejuni regulates electron transport and central metabolic pathways to alter its physiological state during establishment in the chick cecum.

KW - Adaptation, Physiological

KW - Animals

KW - Campylobacter Infections/metabolism

KW - Campylobacter jejuni/genetics

KW - Cecum/microbiology

KW - Chickens/microbiology

KW - Electron Transport

KW - Gene Expression/physiology

KW - Gene Expression Profiling

KW - Oligonucleotide Array Sequence Analysis

KW - Oxygen/metabolism

U2 - 10.1128/IAI.73.8.5278-5285.2005

DO - 10.1128/IAI.73.8.5278-5285.2005

M3 - Article (Academic Journal)

C2 - 16041056

SN - 0019-9567

VL - 73

SP - 5278

EP - 5285

JO - Infection and Immunity

JF - Infection and Immunity

IS - 8

ER -

Campylobacter jejuni gene expression in the chick cecum: evidence for adaptation to a low-oxygen environment

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