Can the optic nerve be repaired?

Alastair Wilkins, Neil Scolding

Research output: Contribution to journalComment/debate (Academic Journal)

284 Downloads (Pure)

Abstract

40 years ago, Bill Blakemore showed that transplanted Schwann cells repaired spinal cord myelin following experimental demyelination.1 The research, presciently funded by the UK Multiple Sclerosis Society, opened the field of cell therapy for multiple sclerosis. Ironically, although this field has developed successfully in various directions, not a single trial of myelinating cell transplantation in multiple sclerosis has been reported in the intervening four decades. Nonetheless, there is a direct link spanning Blakemore's pioneering work and the optic neuritis monoclonal antibody trial RENEW now reported in The Lancet Neurology.
Original languageEnglish
Pages (from-to)172-173
Number of pages2
JournalLancet Neurology
Volume16
Issue number3
Early online date15 Feb 2017
DOIs
Publication statusPublished - Mar 2017

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