Cancer patients’ experiences of using mistletoe (Viscum album): A qualitative systematic review and synthesis

Maggie A Evans, Susan B Bryant, Alyson L Huntley, Gene S Feder

Research output: Contribution to journalArticle (Academic Journal)peer-review

22 Citations (Scopus)
499 Downloads (Pure)


Systematic reviews of mistletoe therapy (MT) trials in cancer show promising results in improvement of patients’ quality of life during chemotherapy and reduction of fatigue. However patients’ experiences of side effects, the acceptability, tolerability and perceived benefits of MT have not been systematically reviewed. The aim of this study is to systematically review and synthesise the results of qualitative studies of cancer patients’ experiences of using MT.

A systematic search was conducted in Medline, Embase, Psychlit, Cinahl and AMED to identify qualitative studies of MT. Articles were screened independently by two reviewers and critically appraised using the CASP tool. A thematic synthesis of the findings was carried out.

173 papers were identified, 156 were excluded at initial screening. Seventeen papers were read in full, 14 of which were excluded. Three articles about patients’ experiences of MT alongside conventional treatment were included in the synthesis, either as a mono-therapy (two articles) or as part of a package of anthroposophic treatment (one article). Patients reported demonstrable changes to their physical, emotional and psycho-social wellbeing following MT, and a reduction in chemo-therapy side-effects. Self-reported side-effects from MT were few, and the studies suggest good adherence to the therapy. Self-injection gave patients a sense of empowerment through involvement in their own treatment.

A systematic search revealed a small number of qualitative studies of MT in cancer. These were effectively combined to provide a detailed overview of patients’ experiences, to complement the developing evidence base from trials. Given the variation in context of MT delivery across the articles it is not possible to ascribe changes in patients’ quality of life specifically to MT. The results of this review will help design outcome measures that more fully capture patients’ experiences. It is essential to embed qualitative research of patients’ experiences of MT and other CAM therapies within future trials.
Original languageEnglish
Pages (from-to)134-144
Number of pages11
JournalJournal of Alternative and Complementary Medicine
Issue number2
Early online date18 Dec 2015
Publication statusPublished - 3 Feb 2016


  • systematic review
  • qualitative synthesis
  • mistletoe
  • cancer


Dive into the research topics of 'Cancer patients’ experiences of using mistletoe (Viscum album): A qualitative systematic review and synthesis'. Together they form a unique fingerprint.

Cite this