Cardiac-motion compensated MR imaging and strain analysis of ventricular trabeculae

Andrew W. Dowsey*, Jennifer Keegan, Guang Zhong Yang

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference Contribution (Conference Proceeding)

2 Citations (Scopus)


In conventional CMR, bulk cardiac motion causes target structures to move in and out of the static acquisition plane. Due to the partial volume effect, accurate localisation of subtle features through the cardiac cycle, such as the trabeculae and papillary muscles, is difficult. This problem is exacerbated by the short acquisition window necessary to avoid motion blur and ghosting, especially during early systole. This paper presents an adaptive imaging approach with COMB multi-tag tracking that follows true 3D motion of the myocardium so that the same tissue slice is imaged throughout the cine acquisition. The technique is demonstrated with motion-compensated multi-slice imaging of ventricles, which allows for tracked visualisation and analysis of the trabeculae and papillary muscles for the first time. This enables novel in-vivo measurement of circumferential and radial strain for trabeculation and papillary muscle contractility. These statistics will facilitate the evaluation of diseases such as mitral valve insufficiency and ischemic heart disease. The adaptive imaging technique will also have significant implications for CMR in general, including motioncompensated quantification of myocardial perfusion and blood flow, and motion-correction of sequences with long acquisition windows.

Original languageEnglish
Title of host publication Medical Image Computing and Computer-Assisted Intervention – MICCAI 2007
Subtitle of host publication10th International Conference, Brisbane, Australia, October 29 - November 2, 2007, Proceedings, Part I
PublisherSpringer Berlin Heidelberg
Number of pages8
ISBN (Electronic)9783540757573
ISBN (Print)9783540757566
Publication statusPublished - 1 Dec 2007
Event10th International Conference on Medical Imaging and Computer-Assisted Intervention, MICCAI 2007 - Brisbane, Australia
Duration: 29 Oct 20072 Nov 2007

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
NumberPART 1
Volume4791 LNCS
ISSN (Print)03029743
ISSN (Electronic)16113349


Conference10th International Conference on Medical Imaging and Computer-Assisted Intervention, MICCAI 2007


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