Cardiac problems in Down syndrome

Lucy Flanders*, Robert Tulloh

*Corresponding author for this work

Research output: Contribution to journalArticle (Academic Journal)peer-review

4 Citations (Scopus)


Children with Down syndrome (DS) have long been known to have an increased incidence of pulmonary arterial hypertension (PAH), but this has not been clearly understood until recently. DS patients have an increased incidence of congenital heart disease (CHD) and upper airway obstruction (UAO) amongst other co-morbidities. Even though CHD is usually quickly recognized in early infancy with current echocardiographic assessment and corrected with early surgery, many children with Down syndrome will still have ongoing PAH which may be unrecognized. A better understanding of the interplay between these conditions, managed by a multi-disciplinary team, is required to maximize their long term quality of life.

Original languageEnglish
Pages (from-to)25-31
Number of pages7
JournalPaediatrics and Child Health
Issue number1
Publication statusPublished - Jan 2011


  • Congenital heart disease
  • Down syndrome
  • Pulmonary hypertension


Dive into the research topics of 'Cardiac problems in Down syndrome'. Together they form a unique fingerprint.

Cite this