Cardiovascular biomarkers and vascular function during childhood in the offspring of mothers with hypertensive disorders of pregnancy: findings from the Avon Longitudinal Study of Parents and Children

Debbie Anne Lawlor, Corrie Macdonald-Wallis, Abigail Fraser, Scott M Nelson, Aroon Hingorani, George Davey Smith, Naveed Sattar, John Deanfield

Research output: Contribution to journalArticle (Academic Journal)

79 Citations (Scopus)

Abstract

It is uncertain if the higher blood pressure (BP) observed in the offspring of hypertensive pregnancies is an isolated abnormality or one that is accompanied by impaired vascular function and alterations in lipid and inflammation markers that would be indicative of a more general cardiometabolic disturbance of the type observed in the mother during pre-eclampsia.
Original languageEnglish
Pages (from-to)335-45
Number of pages11
JournalEuropean Heart Journal
Volume33
Issue number3
DOIs
Publication statusPublished - Feb 2012

Keywords

  • Blood Pressure
  • Humans
  • Vascular Diseases
  • Child
  • Longitudinal Studies
  • Endothelium, Vascular
  • Pregnancy
  • Hypertension, Pregnancy-Induced
  • Prospective Studies
  • Adult
  • Ankle Brachial Index
  • Biological Markers
  • Female
  • Lipid Metabolism

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