Abstract
Objectives: The coexistence of two complex physiologies such as Fontan and pregnancy is still not fully understood. We aim to add a unique and essential knowledge to help our colleagues in the management of Fontan patients that undergo pregnancy as well as the foetus and the placenta perfusion.
Methods and Results: We analyse the coexistence of Fontan and pregnancy physiology on a complex case of a woman with hypoplastic left heart syndrome (HLHS) palliated with a univentricular repair who became pregnant, delivered very prematurely and had atypical placental findings.
Conclusion: Histopathological analysis of the placenta could help us to refine the understanding of Fontan physiology adaptation during pregnancy, predict women and foetal outcomes as well as to plan a better pre-pregnancy status. However, further evidence is needed in order to reach a more solid and unify conclusion.
Methods and Results: We analyse the coexistence of Fontan and pregnancy physiology on a complex case of a woman with hypoplastic left heart syndrome (HLHS) palliated with a univentricular repair who became pregnant, delivered very prematurely and had atypical placental findings.
Conclusion: Histopathological analysis of the placenta could help us to refine the understanding of Fontan physiology adaptation during pregnancy, predict women and foetal outcomes as well as to plan a better pre-pregnancy status. However, further evidence is needed in order to reach a more solid and unify conclusion.
| Original language | English |
|---|---|
| Article number | e001211 |
| Number of pages | 4 |
| Journal | Open Heart |
| Volume | 8 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 19 Feb 2021 |
Research Groups and Themes
- Bristol Heart Institute