Case Report: Leprosy Osteoarticular Alterations Mimicking Rheumatoid Arthritis

Rachel Bertolani do Espírito Santo, Rachel A Serafim, Jurama Barros Gueiros Bitran, Simon M Collin, Patrícia Deps*

*Corresponding author for this work

Research output: Contribution to journalArticle (Academic Journal)peer-review

3 Citations (Scopus)
38 Downloads (Pure)


Deformities of bones of the face and extremities are markers of leprosy (Hansen's disease) which contribute to stigma associated with this disease. Among these deformities are articular alterations that can mimic rheumatoid arthritis (RA). In this case, a 64-year-old man presented with a history of having been treated for lepromatous leprosy and erythema nodosum leprosum episodes, which evolved with joint alterations similar to those of RA. Most cases of leprosy-related arthritis are associated with reactional episodes, of which a large number do not respond to conventional therapy for leprosy reactions. In cases of chronic arthritis not associated with leprosy reactions, although patients show considerable relief with anti-leprosy therapy, arthritis is not completely resolved. This emphasizes the need for early diagnosis and treatment of leprosy to prevent the development of osteoarticular alterations.

Original languageEnglish
Pages (from-to)1316-1318
Number of pages3
JournalAmerican Journal of Tropical Medicine and Hygiene
Issue number6
Early online date30 Mar 2020
Publication statusPublished - 3 Jun 2020


  • Hansen's disease
  • leprosy
  • rheumatoid arthritis
  • erythema nodosum leprosum


Dive into the research topics of 'Case Report: Leprosy Osteoarticular Alterations Mimicking Rheumatoid Arthritis'. Together they form a unique fingerprint.

Cite this