Abstract
Multiple sclerosis (MS) commonly affects the cerebellum causing acute and chronic symptoms. Cerebellar signs contribute significantly to clinical disability, and symptoms such as tremor, ataxia, and dysarthria are particularly difficult to treat. Increasing knowledge concerning the pathophysiology of cerebellar disease in MS from human postmortem studies, experimental models, and clinical trials has raised the hope that cerebellar symptoms will be better treated in the future.
| Original language | English |
|---|---|
| Article number | 312 |
| Number of pages | 6 |
| Journal | Frontiers in Neurology |
| Volume | 8 |
| DOIs | |
| Publication status | Published - 28 Jun 2017 |
Keywords
- multiple sclerosis,
- purkinje cells
- cerebellar diseases,
- ataxia,
- demyelinating diseases,
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This is the final published version of the article (version of record). It first appeared online via Frontiers in Neurology at http://journal.frontiersin.org/article/10.3389/fneur.2017.00312/full#h8 . Please refer to any applicable terms of use of the publisher.