Cerebellar dysfunction in multiple sclerosis

Alastair Wilkins

doi:10.3389/fneur.2017.00312

Cerebellar dysfunction in multiple sclerosis

Alastair Wilkins

Research output: Contribution to journal › Article (Academic Journal) › peer-review

89 Citations (Scopus)

496 Downloads (Pure)

Abstract

Multiple sclerosis (MS) commonly affects the cerebellum causing acute and chronic symptoms. Cerebellar signs contribute significantly to clinical disability, and symptoms such as tremor, ataxia, and dysarthria are particularly difficult to treat. Increasing knowledge concerning the pathophysiology of cerebellar disease in MS from human postmortem studies, experimental models, and clinical trials has raised the hope that cerebellar symptoms will be better treated in the future.

Original language	English
Article number	312
Number of pages	6
Journal	Frontiers in Neurology
Volume	8
DOIs	https://doi.org/10.3389/fneur.2017.00312
Publication status	Published - 28 Jun 2017

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

multiple sclerosis,
purkinje cells
cerebellar diseases,
ataxia,
demyelinating diseases,

Access to Document

10.3389/fneur.2017.00312

Full-text PDF (final published version)
This is the final published version of the article (version of record). It first appeared online via Frontiers in Neurology at http://journal.frontiersin.org/article/10.3389/fneur.2017.00312/full#h8 . Please refer to any applicable terms of use of the publisher.
Final published version, 363 KBLicence: CC BY

Handle.net

Persistent link

Cite this

@article{ac98cba115f1491182d446615b9814ca,

title = "Cerebellar dysfunction in multiple sclerosis",

abstract = "Multiple sclerosis (MS) commonly affects the cerebellum causing acute and chronic symptoms. Cerebellar signs contribute significantly to clinical disability, and symptoms such as tremor, ataxia, and dysarthria are particularly difficult to treat. Increasing knowledge concerning the pathophysiology of cerebellar disease in MS from human postmortem studies, experimental models, and clinical trials has raised the hope that cerebellar symptoms will be better treated in the future.",

keywords = "multiple sclerosis, , purkinje cells , cerebellar diseases, , ataxia, , demyelinating diseases,",

author = "Alastair Wilkins",

year = "2017",

month = jun,

day = "28",

doi = "10.3389/fneur.2017.00312",

language = "English",

volume = "8",

journal = "Frontiers in Neurology",

issn = "1664-2295",

publisher = "Frontiers Media S.A.",

}

TY - JOUR

T1 - Cerebellar dysfunction in multiple sclerosis

AU - Wilkins, Alastair

PY - 2017/6/28

Y1 - 2017/6/28

N2 - Multiple sclerosis (MS) commonly affects the cerebellum causing acute and chronic symptoms. Cerebellar signs contribute significantly to clinical disability, and symptoms such as tremor, ataxia, and dysarthria are particularly difficult to treat. Increasing knowledge concerning the pathophysiology of cerebellar disease in MS from human postmortem studies, experimental models, and clinical trials has raised the hope that cerebellar symptoms will be better treated in the future.

AB - Multiple sclerosis (MS) commonly affects the cerebellum causing acute and chronic symptoms. Cerebellar signs contribute significantly to clinical disability, and symptoms such as tremor, ataxia, and dysarthria are particularly difficult to treat. Increasing knowledge concerning the pathophysiology of cerebellar disease in MS from human postmortem studies, experimental models, and clinical trials has raised the hope that cerebellar symptoms will be better treated in the future.

KW - multiple sclerosis,

KW - purkinje cells

KW - cerebellar diseases,

KW - ataxia,

KW - demyelinating diseases,

U2 - 10.3389/fneur.2017.00312

DO - 10.3389/fneur.2017.00312

M3 - Article (Academic Journal)

C2 - 28701995

SN - 1664-2295

VL - 8

JO - Frontiers in Neurology

JF - Frontiers in Neurology

M1 - 312

ER -

Cerebellar dysfunction in multiple sclerosis

Abstract

UN SDGs

Keywords

Access to Document

Handle.net

Fingerprint

Cite this