Challenges and solutions to recruitment of neonates and children having cardiac surgery into a study using a novel sampling device

Terrie A F Walker-Smith; Daniel P Fudulu; Aravind V Ramesh; Karen Sheehan; Lucy A Culliford; Jon Evans; Gianni D Angelini; Thomas J Upton; Ben J J Gibbison

doi:10.1186/s13104-022-06088-y

Challenges and solutions to recruitment of neonates and children having cardiac surgery into a study using a novel sampling device

Terrie A F Walker-Smith, Daniel P Fudulu, Aravind V Ramesh, Karen Sheehan, Lucy A Culliford, Jon Evans, Gianni D Angelini, Thomas J Upton, Ben J J Gibbison^*

^*Corresponding author for this work

Research output: Contribution to journal › Article (Academic Journal) › peer-review

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Abstract

Objective
To narratively describe the challenges and solutions required in delivering a non-commercial study of children undergoing cardiac surgery using a novel subcutaneous hormone collection device.

Results
The challenges faced by the research team are divided into those of conducting healthcare research in children and those specific to this study. Many of the issues of conducting healthcare research in children can and have been overcome by structural and institutional culture change–normalising and embedding research as part of good clinical care. The issues specific to insertion and maintenance of the novel collection device can be overcome by education and support of the clinical teams. The increased incentives and resources of commercial research may have overcome many of these.

Original language	English
Article number	202
Number of pages	5
Journal	BMC Research Notes
Volume	15
Issue number	1
DOIs	https://doi.org/10.1186/s13104-022-06088-y
Publication status	Published - 11 Jun 2022

Bibliographical note

Funding Information:
This study is funded by the National Institute for Health Research Bristol Biomedical Research Centre and the British Heart Foundation (BHF). The views and opinions expressed therein are those of the author(s) and not necessarily reflect those of the National Institute of Health Research, NHS, the Department of Health and Social Care or the BHF.

Publisher Copyright:
© 2022, The Author(s).

Research Groups and Themes

Bristol Heart Institute
BTC (Bristol Trials Centre)

Keywords

Adrenal
Hypothalamic-pituitary-adrenal axis
Cardiac surgery
Paediatric endocrinology

Access to Document

10.1186/s13104-022-06088-y

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This is the final published version of the article (version of record). It first appeared online via BMC at https://doi.org/10.1186/s13104-022-06088-y .  Please refer to any applicable terms of use of the publisher.
Final published version, 870 KBLicence: CC BY

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Walker-Smith, T. A. F., Fudulu, D. P., Ramesh, A. V., Sheehan, K., Culliford, L. A., Evans, J., Angelini, G. D., Upton, T. J., & Gibbison, B. J. J. (2022). Challenges and solutions to recruitment of neonates and children having cardiac surgery into a study using a novel sampling device. BMC Research Notes, 15(1), Article 202. https://doi.org/10.1186/s13104-022-06088-y

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abstract = "Objective To narratively describe the challenges and solutions required in delivering a non-commercial study of children undergoing cardiac surgery using a novel subcutaneous hormone collection device. Results The challenges faced by the research team are divided into those of conducting healthcare research in children and those specific to this study. Many of the issues of conducting healthcare research in children can and have been overcome by structural and institutional culture change–normalising and embedding research as part of good clinical care. The issues specific to insertion and maintenance of the novel collection device can be overcome by education and support of the clinical teams. The increased incentives and resources of commercial research may have overcome many of these.",

keywords = "Adrenal, Hypothalamic-pituitary-adrenal axis, Cardiac surgery, Paediatric endocrinology",

author = "Walker-Smith, \{Terrie A F\} and Fudulu, \{Daniel P\} and Ramesh, \{Aravind V\} and Karen Sheehan and Culliford, \{Lucy A\} and Jon Evans and Angelini, \{Gianni D\} and Upton, \{Thomas J\} and Gibbison, \{Ben J J\}",

note = "Funding Information: This study is funded by the National Institute for Health Research Bristol Biomedical Research Centre and the British Heart Foundation (BHF). The views and opinions expressed therein are those of the author(s) and not necessarily reflect those of the National Institute of Health Research, NHS, the Department of Health and Social Care or the BHF. Publisher Copyright: {\textcopyright} 2022, The Author(s).",

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doi = "10.1186/s13104-022-06088-y",

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AU - Walker-Smith, Terrie A F

AU - Fudulu, Daniel P

AU - Ramesh, Aravind V

AU - Sheehan, Karen

AU - Culliford, Lucy A

AU - Evans, Jon

AU - Angelini, Gianni D

AU - Upton, Thomas J

AU - Gibbison, Ben J J

N1 - Funding Information: This study is funded by the National Institute for Health Research Bristol Biomedical Research Centre and the British Heart Foundation (BHF). The views and opinions expressed therein are those of the author(s) and not necessarily reflect those of the National Institute of Health Research, NHS, the Department of Health and Social Care or the BHF. Publisher Copyright: © 2022, The Author(s).

PY - 2022/6/11

Y1 - 2022/6/11

N2 - Objective To narratively describe the challenges and solutions required in delivering a non-commercial study of children undergoing cardiac surgery using a novel subcutaneous hormone collection device. Results The challenges faced by the research team are divided into those of conducting healthcare research in children and those specific to this study. Many of the issues of conducting healthcare research in children can and have been overcome by structural and institutional culture change–normalising and embedding research as part of good clinical care. The issues specific to insertion and maintenance of the novel collection device can be overcome by education and support of the clinical teams. The increased incentives and resources of commercial research may have overcome many of these.

AB - Objective To narratively describe the challenges and solutions required in delivering a non-commercial study of children undergoing cardiac surgery using a novel subcutaneous hormone collection device. Results The challenges faced by the research team are divided into those of conducting healthcare research in children and those specific to this study. Many of the issues of conducting healthcare research in children can and have been overcome by structural and institutional culture change–normalising and embedding research as part of good clinical care. The issues specific to insertion and maintenance of the novel collection device can be overcome by education and support of the clinical teams. The increased incentives and resources of commercial research may have overcome many of these.

KW - Adrenal

KW - Hypothalamic-pituitary-adrenal axis

KW - Cardiac surgery

KW - Paediatric endocrinology

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DO - 10.1186/s13104-022-06088-y

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JO - BMC Research Notes

JF - BMC Research Notes

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M1 - 202

ER -

Challenges and solutions to recruitment of neonates and children having cardiac surgery into a study using a novel sampling device

Abstract

Bibliographical note

Research Groups and Themes

Keywords

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