Chapter 11 – Variation, Modification, and Reorganization of Broken Chromatin

Anna Chambers; Jessica  Downs; Timothy Humphrey

Chapter 11 – Variation, Modification, and Reorganization of Broken Chromatin

Anna Chambers, Jessica Downs, Timothy Humphrey

Research output: Chapter in Book/Report/Conference proceeding › Chapter in a book

Abstract

DNA damage occurs in the context of chromatin, and, of course, so do recognition and repair of the DNA lesions. It is well established that chromatin composition and dynamics play a central role in the cellular response to DNA damage and, in particular, to double-strand breaks (DSBs). Here, we review recent advances in the contribution of histone posttranslational modifications, histone variants, and chromatin remodeling enzymes to DSB responses.

Original language	English
Title of host publication	Chromatin Signaling and Diseases
Publisher	Academic Press
Pages	197-216
Publication status	Published - Oct 2016

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Career Development Fellowship - The function of the Irc5 subfamily of chromatin remodelling enzymes in DNA repair.
Chambers, A. L. (Recipient)
1 Oct 2014 → 1 Oct 2017
Activity: Other activity types › Fellowship awarded competitively

Cite this

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title = "Chapter 11 – Variation, Modification, and Reorganization of Broken Chromatin",

abstract = "DNA damage occurs in the context of chromatin, and, of course, so do recognition and repair of the DNA lesions. It is well established that chromatin composition and dynamics play a central role in the cellular response to DNA damage and, in particular, to double-strand breaks (DSBs). Here, we review recent advances in the contribution of histone posttranslational modifications, histone variants, and chromatin remodeling enzymes to DSB responses.",

author = "Anna Chambers and Jessica Downs and Timothy Humphrey",

year = "2016",

month = oct,

language = "English",

pages = "197--216",

booktitle = "Chromatin Signaling and Diseases",

publisher = "Academic Press",

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TY - CHAP

T1 - Chapter 11 – Variation, Modification, and Reorganization of Broken Chromatin

AU - Chambers, Anna

AU - Downs, Jessica

AU - Humphrey, Timothy

PY - 2016/10

Y1 - 2016/10

N2 - DNA damage occurs in the context of chromatin, and, of course, so do recognition and repair of the DNA lesions. It is well established that chromatin composition and dynamics play a central role in the cellular response to DNA damage and, in particular, to double-strand breaks (DSBs). Here, we review recent advances in the contribution of histone posttranslational modifications, histone variants, and chromatin remodeling enzymes to DSB responses.

AB - DNA damage occurs in the context of chromatin, and, of course, so do recognition and repair of the DNA lesions. It is well established that chromatin composition and dynamics play a central role in the cellular response to DNA damage and, in particular, to double-strand breaks (DSBs). Here, we review recent advances in the contribution of histone posttranslational modifications, histone variants, and chromatin remodeling enzymes to DSB responses.

M3 - Chapter in a book

SP - 197

EP - 216

BT - Chromatin Signaling and Diseases

PB - Academic Press

ER -

Chapter 11 – Variation, Modification, and Reorganization of Broken Chromatin

Abstract

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Activities

Career Development Fellowship - The function of the Irc5 subfamily of chromatin remodelling enzymes in DNA repair.

Cite this