Chapter 4: Pathophysiology of Alzheimer's Disease

Shelley J Allen, David Dawbarn

Research output: Chapter in Book/Report/Conference proceedingChapter in a book


• Alzheimer’s disease (AD) is a progressive dementia with loss of neurons and the presence of two main microscopic neuropathological hallmarks: extracellular amyloid plaques and intracellular neurofibrillary tangles

• Early onset AD, the rare familial form, is the result of a mutation in one of three genes
Original languageEnglish
Title of host publicationAlzheimer's Disease
EditorsGunhild Waldemar, Alistair Burns
PublisherOxford University Press
Number of pages8
ISBN (Print)9780199569854
Publication statusPublished - 1 Mar 2009

Publication series

NameOxford Neurology Library
PublisherOxford University Press

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  • Cite this

    Allen, S. J., & Dawbarn, D. (2009). Chapter 4: Pathophysiology of Alzheimer's Disease. In G. Waldemar, & A. Burns (Eds.), Alzheimer's Disease (1st ed., pp. 27-35). (Oxford Neurology Library). Oxford University Press.