Chapter 4: Pathophysiology of Alzheimer's Disease

Shelley J Allen, David Dawbarn

Research output: Chapter in Book/Report/Conference proceedingChapter in a book


• Alzheimer’s disease (AD) is a progressive dementia with loss of neurons and the presence of two main microscopic neuropathological hallmarks: extracellular amyloid plaques and intracellular neurofibrillary tangles

• Early onset AD, the rare familial form, is the result of a mutation in one of three genes
Translated title of the contributionPathophysiology of Alzheimer's Disease
Original languageEnglish
Title of host publicationAlzheimer's Disease
EditorsGunhild Waldemar, Alistair Burns
PublisherOxford University Press
Number of pages8
ISBN (Print)9780199569854
Publication statusPublished - 1 Mar 2009

Publication series

NameOxford Neurology Library
PublisherOxford University Press

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  • Cite this

    Allen, S. J., & Dawbarn, D. (2009). Chapter 4: Pathophysiology of Alzheimer's Disease. In G. Waldemar, & A. Burns (Eds.), Alzheimer's Disease (1st ed., pp. 27-35). (Oxford Neurology Library). Oxford University Press.