Characteristics of men responding to an invitation to undergo testing for prostate cancer as part of a randomised trial

Eleanor I. Walsh; Emma L. Turner; J. Athene Lane; Jenny L. Donovan; David E. Neal; Freddie C. Hamdy; Richard M. Martin; Chris Metcalfe; Jonathan Sterne; Sian Noble; Elizabeth Hill; Siaw Yein Ng; Naomi J Williams; Elizabeth A Down; Eleanor Walsh; Joanna Thorn; Charlotte Davies; Laura Hughes; Mari Anne Rowlands; Lindsey Bell; Yoav Ben-Shlomo; Steven E Oliver; Peter Brindle; Simon Evans; Michael Baum; Peter Albertsen; Tracy Roberts; Mary Robinson; Jan Adolfsson; David Dearnaley; Anthony Zeitman; Fritz Schröder; Tim Peters; Peter Holding; Teresa Lennon; Sue Bonnington; Malcolm Mason; Jon D Oxley; Lars Holmberg; Robert Pickard; Simon Thompson; Usha Menon; Colette Reid; Jon McFarlane; Amit Bahl; Anthony Koupparis; Marta Tazewell; Genevieve Hatton-Brown

doi:10.1186/s13063-016-1624-6

Characteristics of men responding to an invitation to undergo testing for prostate cancer as part of a randomised trial

Eleanor I. Walsh^*, Emma L. Turner, J. Athene Lane, Jenny L. Donovan, David E. Neal, Freddie C. Hamdy, Richard M. Martin, Chris Metcalfe, Jonathan Sterne, Sian Noble, Elizabeth Hill, Siaw Yein Ng, Naomi J Williams, Elizabeth A Down, Eleanor Walsh, Joanna Thorn, Charlotte Davies, Laura Hughes, Mari Anne Rowlands, Lindsey BellYoav Ben-Shlomo, Steven E Oliver, Peter Brindle, Simon Evans, Michael Baum, Peter Albertsen, Tracy Roberts, Mary Robinson, Jan Adolfsson, David Dearnaley, Anthony Zeitman, Fritz Schröder, Tim Peters, Peter Holding, Teresa Lennon, Sue Bonnington, Malcolm Mason, Jon D Oxley, Lars Holmberg, Robert Pickard, Simon Thompson, Usha Menon, Colette Reid, Jon McFarlane, Amit Bahl, Anthony Koupparis, Marta Tazewell, Genevieve Hatton-Brown

^*Corresponding author for this work

Research output: Contribution to journal › Article (Academic Journal) › peer-review

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Abstract

Background
Socio-demographic characteristics are associated with participating in cancer screening and trials. We compared the characteristics of those responding with those not responding to a single invitation for PSA testing for prostate cancer as part of the Cluster randomised triAl of PSA testing for Prostate cancer (CAP).

Methods
Age, rurality and deprivation among 197,763 men from 271 cluster-randomised primary care centres in the UK were compared between those responding (n=90,300) and not responding (n=100,953) to a prostate cancer testing invitation.

Results
There was little difference in age between responders and non-responders. Responders were slightly more likely to come from urban rather than rural areas and were slightly less deprived than those who did not respond.

Conclusion
These data indicate similarities in age and only minor differences in deprivation and urban location between responders and non-responders. These differences were smaller, but in the same direction as observed in other screening trials.

Original language	English
Article number	497
Number of pages	6
Journal	Trials
Volume	17
Issue number	1
DOIs	https://doi.org/10.1186/s13063-016-1624-6
Publication status	Published - 13 Oct 2016

Research Groups and Themes

BTC (Bristol Trials Centre)
BRTC
Centre for Surgical Research

Keywords

Prostate cancer
Prostate specific antigen testing
PSA testing
Randomised controlled trial
Screening

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1186/s13063-016-1624-6

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Walsh, E. I., Turner, E. L., Lane, J. A., Donovan, J. L., Neal, D. E., Hamdy, F. C., Martin, R. M., Metcalfe, C., Sterne, J., Noble, S., Hill, E., Ng, S. Y., Williams, N. J., Down, E. A., Walsh, E., Thorn, J., Davies, C., Hughes, L., Rowlands, M. A., ... Hatton-Brown, G. (2016). Characteristics of men responding to an invitation to undergo testing for prostate cancer as part of a randomised trial. Trials, 17(1), Article 497. https://doi.org/10.1186/s13063-016-1624-6

@article{d98efbe9488a4da7bd8aaa7fa02cae23,

title = "Characteristics of men responding to an invitation to undergo testing for prostate cancer as part of a randomised trial",

abstract = "BackgroundSocio-demographic characteristics are associated with participating in cancer screening and trials. We compared the characteristics of those responding with those not responding to a single invitation for PSA testing for prostate cancer as part of the Cluster randomised triAl of PSA testing for Prostate cancer (CAP).MethodsAge, rurality and deprivation among 197,763 men from 271 cluster-randomised primary care centres in the UK were compared between those responding (n=90,300) and not responding (n=100,953) to a prostate cancer testing invitation.Results There was little difference in age between responders and non-responders. Responders were slightly more likely to come from urban rather than rural areas and were slightly less deprived than those who did not respond. ConclusionThese data indicate similarities in age and only minor differences in deprivation and urban location between responders and non-responders. These differences were smaller, but in the same direction as observed in other screening trials.",

keywords = "Prostate cancer, Prostate specific antigen testing, PSA testing, Randomised controlled trial, Screening",

author = "Walsh, {Eleanor I.} and Turner, {Emma L.} and Lane, {J. Athene} and Donovan, {Jenny L.} and Neal, {David E.} and Hamdy, {Freddie C.} and Martin, {Richard M.} and Chris Metcalfe and Jonathan Sterne and Sian Noble and Elizabeth Hill and Ng, {Siaw Yein} and Williams, {Naomi J} and Down, {Elizabeth A} and Eleanor Walsh and Joanna Thorn and Charlotte Davies and Laura Hughes and Rowlands, {Mari Anne} and Lindsey Bell and Yoav Ben-Shlomo and Oliver, {Steven E} and Peter Brindle and Simon Evans and Michael Baum and Peter Albertsen and Tracy Roberts and Mary Robinson and Jan Adolfsson and David Dearnaley and Anthony Zeitman and Fritz Schr{\"o}der and Tim Peters and Peter Holding and Teresa Lennon and Sue Bonnington and Malcolm Mason and Oxley, {Jon D} and Lars Holmberg and Robert Pickard and Simon Thompson and Usha Menon and Colette Reid and Jon McFarlane and Amit Bahl and Anthony Koupparis and Marta Tazewell and Genevieve Hatton-Brown",

year = "2016",

month = oct,

day = "13",

doi = "10.1186/s13063-016-1624-6",

language = "English",

volume = "17",

journal = "Trials",

issn = "1745-6215",

publisher = "BioMed Central",

number = "1",

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Walsh, EI , Turner, EL , Lane, JA , Donovan, JL, Neal, DE, Hamdy, FC, Martin, RM , Metcalfe, C , Sterne, J , Noble, S , Hill, E, Ng, SY, Williams, NJ, Down, EA, Walsh, E , Thorn, J , Davies, C, Hughes, L, Rowlands, MA, Bell, L, Ben-Shlomo, Y, Oliver, SE, Brindle, P, Evans, S, Baum, M, Albertsen, P, Roberts, T, Robinson, M, Adolfsson, J, Dearnaley, D, Zeitman, A, Schröder, F, Peters, T, Holding, P, Lennon, T, Bonnington, S, Mason, M, Oxley, JD, Holmberg, L, Pickard, R, Thompson, S, Menon, U, Reid, C, McFarlane, J, Bahl, A, Koupparis, A, Tazewell, M & Hatton-Brown, G 2016, 'Characteristics of men responding to an invitation to undergo testing for prostate cancer as part of a randomised trial', Trials, vol. 17, no. 1, 497. https://doi.org/10.1186/s13063-016-1624-6

TY - JOUR

T1 - Characteristics of men responding to an invitation to undergo testing for prostate cancer as part of a randomised trial

AU - Walsh, Eleanor I.

AU - Turner, Emma L.

AU - Lane, J. Athene

AU - Donovan, Jenny L.

AU - Neal, David E.

AU - Hamdy, Freddie C.

AU - Martin, Richard M.

AU - Metcalfe, Chris

AU - Sterne, Jonathan

AU - Noble, Sian

AU - Hill, Elizabeth

AU - Ng, Siaw Yein

AU - Williams, Naomi J

AU - Down, Elizabeth A

AU - Walsh, Eleanor

AU - Thorn, Joanna

AU - Davies, Charlotte

AU - Hughes, Laura

AU - Rowlands, Mari Anne

AU - Bell, Lindsey

AU - Ben-Shlomo, Yoav

AU - Oliver, Steven E

AU - Brindle, Peter

AU - Evans, Simon

AU - Baum, Michael

AU - Albertsen, Peter

AU - Roberts, Tracy

AU - Robinson, Mary

AU - Adolfsson, Jan

AU - Dearnaley, David

AU - Zeitman, Anthony

AU - Schröder, Fritz

AU - Peters, Tim

AU - Holding, Peter

AU - Lennon, Teresa

AU - Bonnington, Sue

AU - Mason, Malcolm

AU - Oxley, Jon D

AU - Holmberg, Lars

AU - Pickard, Robert

AU - Thompson, Simon

AU - Menon, Usha

AU - Reid, Colette

AU - McFarlane, Jon

AU - Bahl, Amit

AU - Koupparis, Anthony

AU - Tazewell, Marta

AU - Hatton-Brown, Genevieve

PY - 2016/10/13

Y1 - 2016/10/13

N2 - BackgroundSocio-demographic characteristics are associated with participating in cancer screening and trials. We compared the characteristics of those responding with those not responding to a single invitation for PSA testing for prostate cancer as part of the Cluster randomised triAl of PSA testing for Prostate cancer (CAP).MethodsAge, rurality and deprivation among 197,763 men from 271 cluster-randomised primary care centres in the UK were compared between those responding (n=90,300) and not responding (n=100,953) to a prostate cancer testing invitation.Results There was little difference in age between responders and non-responders. Responders were slightly more likely to come from urban rather than rural areas and were slightly less deprived than those who did not respond. ConclusionThese data indicate similarities in age and only minor differences in deprivation and urban location between responders and non-responders. These differences were smaller, but in the same direction as observed in other screening trials.

AB - BackgroundSocio-demographic characteristics are associated with participating in cancer screening and trials. We compared the characteristics of those responding with those not responding to a single invitation for PSA testing for prostate cancer as part of the Cluster randomised triAl of PSA testing for Prostate cancer (CAP).MethodsAge, rurality and deprivation among 197,763 men from 271 cluster-randomised primary care centres in the UK were compared between those responding (n=90,300) and not responding (n=100,953) to a prostate cancer testing invitation.Results There was little difference in age between responders and non-responders. Responders were slightly more likely to come from urban rather than rural areas and were slightly less deprived than those who did not respond. ConclusionThese data indicate similarities in age and only minor differences in deprivation and urban location between responders and non-responders. These differences were smaller, but in the same direction as observed in other screening trials.

KW - Prostate cancer

KW - Prostate specific antigen testing

KW - PSA testing

KW - Randomised controlled trial

KW - Screening

UR - http://www.scopus.com/inward/record.url?scp=84992089345&partnerID=8YFLogxK

U2 - 10.1186/s13063-016-1624-6

DO - 10.1186/s13063-016-1624-6

M3 - Article (Academic Journal)

C2 - 27737692

AN - SCOPUS:84992089345

SN - 1745-6215

VL - 17

JO - Trials

JF - Trials

IS - 1

M1 - 497

ER -

Characteristics of men responding to an invitation to undergo testing for prostate cancer as part of a randomised trial

Abstract

Research Groups and Themes

Keywords

UN SDGs

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