Chemical communication in spatially organized protocell colonies and protocell/living cell micro-arrays

Xuejing Wang; Liangfei Tian; Hang Du; Mei Li; Wei Mu; Bruce W. Drinkwater; Xiaojun Han; Stephen Mann

doi:10.1039/c9sc04522h

Chemical communication in spatially organized protocell colonies and protocell/living cell micro-arrays

Xuejing Wang, Liangfei Tian, Hang Du, Mei Li, Wei Mu, Bruce W. Drinkwater, Xiaojun Han^*, Stephen Mann

^*Corresponding author for this work

Research output: Contribution to journal › Article (Academic Journal) › peer-review

96 Citations (Scopus)

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Abstract

Micro-arrays of discrete or hemifused giant unilamellar lipid vesicles (GUVs) with controllable spatial geometries, lattice dimensions, trapped occupancies and compositions are prepared by acoustic standing wave patterning, and employed as platforms to implement chemical signaling in GUV colonies and protocell/living cell consortia. The methodology offers an alternative approach to GUV micro-array fabrication and provides new opportunities in protocell research and bottom-up synthetic biology.

Original language	English
Pages (from-to)	9446-9453
Number of pages	8
Journal	Chemical Science
Volume	10
Issue number	41
Early online date	18 Sept 2019
DOIs	https://doi.org/10.1039/c9sc04522h
Publication status	E-pub ahead of print - 18 Sept 2019

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BrisSynBio
Bristol BioDesign Institute

Keywords

Synthetic biology

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10.1039/c9sc04522h

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This is the final published version of the article (version of record). It first appeared online via Royal Society of Chemistry at https://doi.org/10.1039/C9SC04522H . Please refer to any applicable terms of use of the publisher.
Final published version, 1.93 MBLicence: CC BY-NC

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abstract = "Micro-arrays of discrete or hemifused giant unilamellar lipid vesicles (GUVs) with controllable spatial geometries, lattice dimensions, trapped occupancies and compositions are prepared by acoustic standing wave patterning, and employed as platforms to implement chemical signaling in GUV colonies and protocell/living cell consortia. The methodology offers an alternative approach to GUV micro-array fabrication and provides new opportunities in protocell research and bottom-up synthetic biology.",

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AU - Wang, Xuejing

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AU - Du, Hang

AU - Li, Mei

AU - Mu, Wei

AU - Drinkwater, Bruce W.

AU - Han, Xiaojun

AU - Mann, Stephen

PY - 2019/9/18

Y1 - 2019/9/18

N2 - Micro-arrays of discrete or hemifused giant unilamellar lipid vesicles (GUVs) with controllable spatial geometries, lattice dimensions, trapped occupancies and compositions are prepared by acoustic standing wave patterning, and employed as platforms to implement chemical signaling in GUV colonies and protocell/living cell consortia. The methodology offers an alternative approach to GUV micro-array fabrication and provides new opportunities in protocell research and bottom-up synthetic biology.

AB - Micro-arrays of discrete or hemifused giant unilamellar lipid vesicles (GUVs) with controllable spatial geometries, lattice dimensions, trapped occupancies and compositions are prepared by acoustic standing wave patterning, and employed as platforms to implement chemical signaling in GUV colonies and protocell/living cell consortia. The methodology offers an alternative approach to GUV micro-array fabrication and provides new opportunities in protocell research and bottom-up synthetic biology.

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SN - 2041-6520

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SP - 9446

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JO - Chemical Science

JF - Chemical Science

IS - 41

ER -

Chemical communication in spatially organized protocell colonies and protocell/living cell micro-arrays

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BrisSynBio: Bristol Centre for Synthetic Biology

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Chemical communication in spatially organized protocell colonies and protocell/living cell micro-arrays

Abstract

Research Groups and Themes

Keywords

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BrisSynBio: Bristol Centre for Synthetic Biology

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