Chemical degradation of BTK/TEC as a novel approach to inhibit platelet function

Justin S Trory; Attila Munkacsi; Kamila Sledz; Lucy Goudswaard; Molly L Jackson; Kate J Heesom; Samantha Frances Moore; Alastair W Poole; Benham Nabet; Varinder K Aggarwal; Ingeborg Hers

doi:10.1182/bloodadvances.2022008466

Chemical degradation of BTK/TEC as a novel approach to inhibit platelet function

Justin S Trory, Attila Munkacsi, Kamila Sledz, Lucy Goudswaard, Molly L Jackson, Kate J Heesom, Samantha Frances Moore, Alastair W Poole, Benham Nabet, Varinder K Aggarwal, Ingeborg Hers^*

^*Corresponding author for this work

Research output: Contribution to journal › Letter (Academic Journal) › peer-review

4 Citations (Scopus)

Original language	English
Journal	Blood Advances
Early online date	7 Nov 2022
DOIs	https://doi.org/10.1182/bloodadvances.2022008466
Publication status	Published - 9 May 2023

Bibliographical note

Research Groups and Themes

Organic & Biological

Access to Document

10.1182/bloodadvances.2022008466Licence: CC BY-NC-ND

Handle.net

Persistent link

Embargoed Document

Full-text PDF (accepted manuscript)
Accepted author manuscript, 2.72 MB

Embargoed Document

Supplementary information PDF
Accepted author manuscript, 554 KB

PROTACs as a novel approach to target tyrosine kinases for degradation in human platelets
Hers, I. (Principal Investigator)
1/10/23 → 30/09/26
Project: Research, Parent

Cite this

@article{8bc6a18deed546cea568b76fdf0a91db,

title = "Chemical degradation of BTK/TEC as a novel approach to inhibit platelet function",

author = "Trory, \{Justin S\} and Attila Munkacsi and Kamila Sledz and Lucy Goudswaard and Jackson, \{Molly L\} and Heesom, \{Kate J\} and Moore, \{Samantha Frances\} and Poole, \{Alastair W\} and Benham Nabet and Aggarwal, \{Varinder K\} and Ingeborg Hers",

note = "{\textcopyright} 2023 by The American Society of Hematology.",

year = "2023",

month = may,

day = "9",

doi = "10.1182/bloodadvances.2022008466",

language = "English",

journal = "Blood Advances",

issn = "2473-9529",

publisher = "American Society of Hematology",

}

TY - JOUR

T1 - Chemical degradation of BTK/TEC as a novel approach to inhibit platelet function

AU - Trory, Justin S

AU - Munkacsi, Attila

AU - Sledz, Kamila

AU - Goudswaard, Lucy

AU - Jackson, Molly L

AU - Heesom, Kate J

AU - Moore, Samantha Frances

AU - Poole, Alastair W

AU - Nabet, Benham

AU - Aggarwal, Varinder K

AU - Hers, Ingeborg

PY - 2023/5/9

Y1 - 2023/5/9

U2 - 10.1182/bloodadvances.2022008466

DO - 10.1182/bloodadvances.2022008466

M3 - Letter (Academic Journal)

C2 - 36342848

SN - 2473-9529

JO - Blood Advances

JF - Blood Advances

ER -

Chemical degradation of BTK/TEC as a novel approach to inhibit platelet function

Bibliographical note

Research Groups and Themes

Access to Document

Handle.net

Embargoed Document

Embargoed Document

Projects

PROTACs as a novel approach to target tyrosine kinases for degradation in human platelets

Cite this