Childhood empyema: limited potential impact of 7-valent pneumococcal conjugate vaccine

Margaret Fletcher; John Leeming; Keith Cartwright; Adam Finn; South West of England Invasive Community Acquired Infection Study Group

doi:10.1097/01.inf.0000219535.14201.1b

Childhood empyema: limited potential impact of 7-valent pneumococcal conjugate vaccine

Margaret Fletcher, John Leeming, Keith Cartwright, Adam Finn, South West of England Invasive Community Acquired Infection Study Group

Research output: Contribution to journal › Article (Academic Journal) › peer-review

57 Citations (Scopus)

Abstract

During 2003–2004, locally presenting pleural empyema cases in children increased 3-fold. Antigen analysis of empyema fluid identified Streptococcus pneumoniae in 27 of 29 cases for whom samples were available and capsular polysaccharide type 1 in 18 of these. Use of a conjugate vaccine without serotype 1 antigen would have had limited impact on this morbidity in our region.

Translated title of the contribution	Childhood empyema: limited potential impact of 7-valent pneumococcal conjugate vaccine
Original language	English
Pages (from-to)	559 - 560
Number of pages	2
Journal	Pediatric Infectious Disease Journal
Volume	25
Issue number	6
DOIs	https://doi.org/10.1097/01.inf.0000219535.14201.1b
Publication status	Published - Jun 2006

Bibliographical note

Publisher: Lippincott Williams & Wilkins
Other: (on behalf of the South West of England Invasive Community acquired Infection Study Group

Keywords

Empyema, Pleural
Humans
Child
Immunity
Pneumococcal Infections
Great Britain
Risk Assessment
Age Distribution
Child, Preschool
Vaccines, Conjugate
Streptococcus pneumoniae
Pneumococcal Vaccines
Prospective Studies
Antibodies, Bacterial
Enzyme-Linked Immunosorbent Assay
Incidence
Follow-Up Studies
Female
Male

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1097/01.inf.0000219535.14201.1b

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@article{3e249281237e4f20aba263db1180d517,

title = "Childhood empyema: limited potential impact of 7-valent pneumococcal conjugate vaccine",

abstract = "During 2003–2004, locally presenting pleural empyema cases in children increased 3-fold. Antigen analysis of empyema fluid identified Streptococcus pneumoniae in 27 of 29 cases for whom samples were available and capsular polysaccharide type 1 in 18 of these. Use of a conjugate vaccine without serotype 1 antigen would have had limited impact on this morbidity in our region.",

keywords = "Empyema, Pleural, Humans, Child, Immunity, Pneumococcal Infections, Great Britain, Risk Assessment, Age Distribution, Child, Preschool, Vaccines, Conjugate, Streptococcus pneumoniae, Pneumococcal Vaccines, Prospective Studies, Antibodies, Bacterial, Enzyme-Linked Immunosorbent Assay, Incidence, Follow-Up Studies, Female, Male",

author = "Margaret Fletcher and John Leeming and Keith Cartwright and Adam Finn and {South West of England Invasive Community Acquired Infection Study Group}",

note = "Publisher: Lippincott Williams & Wilkins Other: (on behalf of the South West of England Invasive Community acquired Infection Study Group",

year = "2006",

month = jun,

doi = "10.1097/01.inf.0000219535.14201.1b",

language = "English",

volume = "25",

pages = "559 -- 560",

journal = "Pediatric Infectious Disease Journal",

issn = "0891-3668",

publisher = "Lippincott Williams and Wilkins",

number = "6",

}

TY - JOUR

T1 - Childhood empyema: limited potential impact of 7-valent pneumococcal conjugate vaccine

AU - Fletcher, Margaret

AU - Leeming, John

AU - Cartwright, Keith

AU - Finn, Adam

AU - South West of England Invasive Community Acquired Infection Study Group

N1 - Publisher: Lippincott Williams & Wilkins Other: (on behalf of the South West of England Invasive Community acquired Infection Study Group

PY - 2006/6

Y1 - 2006/6

N2 - During 2003–2004, locally presenting pleural empyema cases in children increased 3-fold. Antigen analysis of empyema fluid identified Streptococcus pneumoniae in 27 of 29 cases for whom samples were available and capsular polysaccharide type 1 in 18 of these. Use of a conjugate vaccine without serotype 1 antigen would have had limited impact on this morbidity in our region.

AB - During 2003–2004, locally presenting pleural empyema cases in children increased 3-fold. Antigen analysis of empyema fluid identified Streptococcus pneumoniae in 27 of 29 cases for whom samples were available and capsular polysaccharide type 1 in 18 of these. Use of a conjugate vaccine without serotype 1 antigen would have had limited impact on this morbidity in our region.

KW - Empyema, Pleural

KW - Humans

KW - Child

KW - Immunity

KW - Pneumococcal Infections

KW - Great Britain

KW - Risk Assessment

KW - Age Distribution

KW - Child, Preschool

KW - Vaccines, Conjugate

KW - Streptococcus pneumoniae

KW - Pneumococcal Vaccines

KW - Prospective Studies

KW - Antibodies, Bacterial

KW - Enzyme-Linked Immunosorbent Assay

KW - Incidence

KW - Follow-Up Studies

KW - Female

KW - Male

U2 - 10.1097/01.inf.0000219535.14201.1b

DO - 10.1097/01.inf.0000219535.14201.1b

M3 - Article (Academic Journal)

C2 - 16732158

SN - 0891-3668

VL - 25

SP - 559

EP - 560

JO - Pediatric Infectious Disease Journal

JF - Pediatric Infectious Disease Journal

IS - 6

ER -

Childhood empyema: limited potential impact of 7-valent pneumococcal conjugate vaccine

Abstract

Bibliographical note

Keywords

UN SDGs

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