Chronic maladaptive pain in cats: A review of current and future drug treatment options

Derek Adrian, Mark Papich, Ron Baynes, Jo Murrell, B. Duncan X. Lascelles

Research output: Contribution to journalArticle (Academic Journal)peer-review

15 Citations (Scopus)
683 Downloads (Pure)


Despite our increasing understanding of the pathophysiology underlying chronic or maladaptive pain, there is a significant gap in our ability to diagnose and treat the condition in domestic cats. Newer techniques being used to identify abnormalities in pain processing in the cat include validated owner questionnaires, measurement of movement and activity, and measurement of sensory thresholds and somatomotor responses. While some data are available evaluating possible therapeutics for the treatment of chronic pain in the cat, most data are limited to normal cats. This review details our current understanding of chronic or maladaptive pain, techniques for the detection and measurement of the condition and the associated central nervous changes, as well as an overview of the data evaluating potential therapeutics in cats.
Original languageEnglish
Pages (from-to)52-61
Number of pages10
JournalVeterinary Journal
Early online date20 Aug 2017
Publication statusPublished - 10 Dec 2017


  • Maladaptive pain
  • Cats
  • Analgesia
  • Central plasticity
  • Chronic pain


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