Circadian oscillations of cytosolic free calcium regulate the Arabidopsis circadian clock

María Carmen Martí Ruiz, Katharine E. Hubbard, Michael J. Gardner, Hyun Ju Jung, Sylvain Aubry, Carlos T. Hotta, Nur Izzati Mohd-Noh, Fiona C. Robertson, Timothy J. Hearn, Yu Chang Tsai, Antony N. Dodd, Matthew Hannah, Isabelle A. Carré, Julia M. Davies, Janet Braam, Alex A.R. Webb*

*Corresponding author for this work

Research output: Contribution to journalArticle (Academic Journal)peer-review

22 Citations (Scopus)
289 Downloads (Pure)

Abstract

In the last decade, the view of circadian oscillators has expanded from transcriptional feedback to incorporate post-transcriptional, post-translational, metabolic processes and ionic signalling. In plants and animals, there are circadian oscillations in the concentration of cytosolic free Ca2+ ([Ca2+]cyt), though their purpose has not been fully characterized. We investigated whether circadian oscillations of [Ca2+]cyt regulate the circadian oscillator of Arabidopsis thaliana. We report that in Arabidopsis, [Ca2+]cyt circadian oscillations can regulate circadian clock function through the Ca2+-dependent action of CALMODULIN-LIKE24 (CML24). Genetic analyses demonstrate a linkage between CML24 and the circadian oscillator, through pathways involving the circadian oscillator gene TIMING OF CAB2 EXPRESSION1 (TOC1).

Original languageEnglish
Pages (from-to)690-698
Number of pages9
JournalNature Plants
Volume4
Issue number9
Early online date20 Aug 2018
DOIs
Publication statusPublished - Sep 2018

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