Idiopathic pulmonary fibrosis (IPF) is a chronic, interstitial lung disease primarily affecting West Highland White Terriers (WHWTs).
To describe the clinicopathological and diagnostic imaging features in WHWTs with IPF.
Twelve WHWTs with IPF and 14 healthy control WHWTs.
Prospective study. Clinical signs and findings of physical examination, blood and arterial blood gas analyses, radiography, high-resolution computed tomography (HRCT), bronchoscopy and bronchoalveolar lavage (BAL) of IPF dogs were obtained and compared with controls. Histopathologic changes in IPF dogs were evaluated.
Mean partial pressure of oxygen was significantly lower in IPF (mean +/- SD, 65.5 +/- 15.4 mmHg) than in controls (99.1 +/- 7.8 mmHg, P
Conclusion and Clinical Importance
IPF causes substantial hypoxemia. In HRCT, GGO is a consistent finding. IPF dogs have concurrent airway changes and an increase in BALF TCC.
- High-resolution computed tomography
- Interstitial lung disease
- USUAL INTERSTITIAL PNEUMONIA
- Bronchoalveolar lavage
- BRONCHOALVEOLAR LAVAGE
- Arterial blood gases