Clinical impact and reliability of pleural fluid mesothelin in undiagnosed pleural effusions

HE Davies, RS Sadler, S Bielsa, NA Maskell, NM Rahman, RJ Davies, BL Ferry, YC Lee

Research output: Contribution to journalArticle (Academic Journal)peer-review

86 Citations (Scopus)

Abstract

Serum mesothelin is a new biomarker for the diagnosis of mesothelioma. Patients with mesothelioma commonly present with pleural effusions. To define the clinical utility of mesothelin quantification in pleural fluid, we assessed its additional value over pleural fluid cytology and its short-term reproducibility and reliability after pleural inflammatory processes, including pleurodesis.
Translated title of the contributionClinical Impact and Reliability of Pleural Fluid Mesothelin in Undiagnosed Pleural Effusions
Original languageEnglish
Pages (from-to)437 - 444
Number of pages8
JournalAmerican Journal of Respiratory and Critical Care Medicine
Volume180
Issue number5
DOIs
Publication statusPublished - Sep 2009

Bibliographical note

Other identifier: PMID: 19299498

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