TY - JOUR
T1 - Co-electrospun brain mimetic hollow microfibres fibres for diffusion magnetic resonance imaging
AU - Zhou, FL
AU - Hubbard Cristinacce, PL
AU - Eichhorn, SJ
AU - Parker, GJM
PY - 2015/1/1
Y1 - 2015/1/1
N2 - © Springer International Publishing Switzerland 2015. Diffusion magnetic resonance imaging (dMRI) provides a non-invasive tool to explore biological tissues, including brain with its highly organised hierarchical fibrous structures. An MR phantom is a test object with known size and material for the calibration of MR scanners and the validation of image processing algorithms. Despite extensive research on the development of brain-mimicking phantoms, there are significant problems with using the existing phantoms for dMRI. This chapter is designed to lead the reader through the development of brain-mimetic phantoms for application in dMRI. Our starting point is a brief introduction to the dMRI technique and phantoms previously developed to mimic brain tissues. The second section focuses on the preparation and characterization of novel physical phantoms composed of co-electrospun hollow microfibres. Finally, the evaluation of the developed co-electrospun phantoms is presented in the third section.
AB - © Springer International Publishing Switzerland 2015. Diffusion magnetic resonance imaging (dMRI) provides a non-invasive tool to explore biological tissues, including brain with its highly organised hierarchical fibrous structures. An MR phantom is a test object with known size and material for the calibration of MR scanners and the validation of image processing algorithms. Despite extensive research on the development of brain-mimicking phantoms, there are significant problems with using the existing phantoms for dMRI. This chapter is designed to lead the reader through the development of brain-mimetic phantoms for application in dMRI. Our starting point is a brief introduction to the dMRI technique and phantoms previously developed to mimic brain tissues. The second section focuses on the preparation and characterization of novel physical phantoms composed of co-electrospun hollow microfibres. Finally, the evaluation of the developed co-electrospun phantoms is presented in the third section.
U2 - 10.1007/978-3-319-14406-1_12
DO - 10.1007/978-3-319-14406-1_12
M3 - Article (Academic Journal)
SN - 1434-4904
VL - 96
SP - 289
EP - 304
JO - NanoScience and Technology
JF - NanoScience and Technology
ER -