Cobalt-Catalyzed Suzuki Biaryl Coupling of Aryl Halides

Soneela Asghar; Sanita B. Tailor; David Elorriaga; Robin B. Bedford

doi:10.1002/anie.201710053

Cobalt-Catalyzed Suzuki Biaryl Coupling of Aryl Halides

Soneela Asghar, Sanita B. Tailor, David Elorriaga, Robin B. Bedford^*

^*Corresponding author for this work

Research output: Contribution to journal › Article (Academic Journal) › peer-review

69 Citations (Scopus)

495 Downloads (Pure)

Abstract

Readily accessed cobalt pre-catalysts with N-heterocyclic carbene ligands catalyze the Suzuki cross-coupling of aryl chlorides and bromides with alkyllithium-activated arylboronic pinacolate esters. Preliminary mechanistic studies indicate that the cobalt species is reduced to Co⁰ during the reaction.

Original language	English
Pages (from-to)	16367-16370
Number of pages	4
Journal	Angewandte Chemie - International Edition
Volume	56
Issue number	51
Early online date	14 Nov 2017
DOIs	https://doi.org/10.1002/anie.201710053
Publication status	Published - 18 Dec 2017

Keywords

aryl halides
carbenes
cobalt
N-heterocycles
Suzuki coupling

Access to Document

10.1002/anie.201710053

Full-text PDF (final published version)Final published version, 1.17 MBLicence: CC BY

Handle.net

Persistent link

Cite this

@article{55490513d2044d2c9c37ba655cd8b6a6,

title = "Cobalt-Catalyzed Suzuki Biaryl Coupling of Aryl Halides",

abstract = "Readily accessed cobalt pre-catalysts with N-heterocyclic carbene ligands catalyze the Suzuki cross-coupling of aryl chlorides and bromides with alkyllithium-activated arylboronic pinacolate esters. Preliminary mechanistic studies indicate that the cobalt species is reduced to Co0 during the reaction.",

keywords = "aryl halides, carbenes, cobalt, N-heterocycles, Suzuki coupling",

author = "Soneela Asghar and Tailor, {Sanita B.} and David Elorriaga and Bedford, {Robin B.}",

year = "2017",

month = dec,

day = "18",

doi = "10.1002/anie.201710053",

language = "English",

volume = "56",

pages = "16367--16370",

journal = "Angewandte Chemie - International Edition",

issn = "1433-7851",

publisher = "Wiley-VCH Verlag",

number = "51",

}

TY - JOUR

T1 - Cobalt-Catalyzed Suzuki Biaryl Coupling of Aryl Halides

AU - Asghar, Soneela

AU - Tailor, Sanita B.

AU - Elorriaga, David

AU - Bedford, Robin B.

PY - 2017/12/18

Y1 - 2017/12/18

N2 - Readily accessed cobalt pre-catalysts with N-heterocyclic carbene ligands catalyze the Suzuki cross-coupling of aryl chlorides and bromides with alkyllithium-activated arylboronic pinacolate esters. Preliminary mechanistic studies indicate that the cobalt species is reduced to Co0 during the reaction.

AB - Readily accessed cobalt pre-catalysts with N-heterocyclic carbene ligands catalyze the Suzuki cross-coupling of aryl chlorides and bromides with alkyllithium-activated arylboronic pinacolate esters. Preliminary mechanistic studies indicate that the cobalt species is reduced to Co0 during the reaction.

KW - aryl halides

KW - carbenes

KW - cobalt

KW - N-heterocycles

KW - Suzuki coupling

UR - http://www.scopus.com/inward/record.url?scp=85036527523&partnerID=8YFLogxK

U2 - 10.1002/anie.201710053

DO - 10.1002/anie.201710053

M3 - Article (Academic Journal)

C2 - 29135071

SN - 1433-7851

VL - 56

SP - 16367

EP - 16370

JO - Angewandte Chemie - International Edition

JF - Angewandte Chemie - International Edition

IS - 51

ER -

Cobalt-Catalyzed Suzuki Biaryl Coupling of Aryl Halides

Abstract

Keywords

Access to Document

Handle.net

Other files and links

Fingerprint

The Ironworks: a mechanistic foundry for iron-catalysed cross-coupling

3-month Core Capability for Chemistry Research

Professor Robin B Bedford

Cite this

Cobalt-Catalyzed Suzuki Biaryl Coupling of Aryl Halides

Abstract

Keywords

Access to Document

Handle.net

Other files and links

Fingerprint

Projects

The Ironworks: a mechanistic foundry for iron-catalysed cross-coupling

3-month Core Capability for Chemistry Research

Profiles

Professor Robin B Bedford

Cite this