Cohort Profile: Nausea and vomiting during pregnancy genetics consortium (NVP Genetics Consortium)

Lucia Colodro-Conde, Simone M Cross, Penelope A Lind, Jodie N Painter, Annika Gunst, Patrick Jern, Ada Johansson, Merete Lund Maegbaek, Trine Munk-Olsen, Dale R Nyholt, Juan R Ordoñana, Lavinia Paternoster, Juan F Sánchez-Romera, Margaret J Wright, Sarah E Medland

Research output: Contribution to journalArticle (Academic Journal)

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Abstract

Nausea and vomiting during pregnancy (NVP), commonly known as morning sickness, is very common and is typically self-limiting. However, more severe forms and the development of hyperemesis gravidarum (HG), defined as persistent and excessive vomiting, with dehydration, ketonuria and >5% bodyweight loss,1 may lead to health consequences for the mother and the offspring exposed in utero. Despite efforts towards understanding the causes of NVP and HG, they are not well established. The NVP Genetics Consortium is an open collaborative network of researchers integrating data on NVP of women who have been pregnant at least once, with the goal of investigating NVP, NVP severity and HG. Currently, the NVP Genetics Consortium brings together data from Australia, Finland, Spain, the UK and Denmark. The Consortium is actively recruiting new members.
Original languageEnglish
Article numbere17
Number of pages8
JournalInternational Journal of Epidemiology
Volume46
Issue number2
Early online date26 Feb 2016
DOIs
Publication statusPublished - Apr 2017

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    Colodro-Conde, L., Cross, S. M., Lind, P. A., Painter, J. N., Gunst, A., Jern, P., Johansson, A., Maegbaek, M. L., Munk-Olsen, T., Nyholt, D. R., Ordoñana, J. R., Paternoster, L., Sánchez-Romera, J. F., Wright, M. J., & Medland, S. E. (2017). Cohort Profile: Nausea and vomiting during pregnancy genetics consortium (NVP Genetics Consortium). International Journal of Epidemiology, 46(2), [e17]. https://doi.org/10.1093/ije/dyv360