Abstract
For the 500 000 new cases of colorectal cancer in the world each year, identification of patients with a worse prognosis and those who are more likely to respond to treatment is a challenge. There is an increasing body of evidence correlating genetic mutations with outcome in tumours derived from human colorectal cancer cohorts. K-ras, but not p53 or APC, mutations appear to be associated with poorer overall survival in colorectal cancer patients.
| Translated title of the contribution | Colorectal cancer prognosis: is it all mutation, mutation, mutation? |
|---|---|
| Original language | English |
| Pages (from-to) | 1209 - 1211 |
| Number of pages | 2 |
| Journal | Gut |
| Volume | 54 |
| Publication status | Published - Sep 2005 |