Colorectal cancer prognosis: is it all mutation, mutation, mutation?

AB Hassan, C Paraskeva

Research output: Contribution to journalArticle (Academic Journal)

9 Citations (Scopus)

Abstract

For the 500 000 new cases of colorectal cancer in the world each year, identification of patients with a worse prognosis and those who are more likely to respond to treatment is a challenge. There is an increasing body of evidence correlating genetic mutations with outcome in tumours derived from human colorectal cancer cohorts. K-ras, but not p53 or APC, mutations appear to be associated with poorer overall survival in colorectal cancer patients.
Translated title of the contributionColorectal cancer prognosis: is it all mutation, mutation, mutation?
Original languageEnglish
Pages (from-to)1209 - 1211
Number of pages2
JournalGut
Volume54
Publication statusPublished - Sep 2005

Bibliographical note

Other: Review-leading article

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