Comparative finite-element analysis: a single computational modelling method can estimate the mechanical properties of porcine and human vertebrae

K. Robson Brown*, S. Tarsuslugil, V. N. Wijayathunga, R. K. Wilcox

*Corresponding author for this work

Research output: Contribution to journalArticle (Academic Journal)peer-review

9 Citations (Scopus)

Abstract

Significant advances in the functional analysis of musculoskeletal systems require the development of modelling techniques with improved focus, accuracy and validity. This need is particularly visible in the fields, such as palaeontology, where unobservable parameters may lie at the heart of the most interesting research questions, and where models and simulations may provide some of the most innovative solutions. Here, we report on the development of a computational modelling method to generate estimates of the mechanical properties of vertebral bone across two living species, using elderly human and juvenile porcine specimens as cases with very different levels of bone volume fraction and mineralization. This study is presented in two parts; part I presents the computational model development and validation, and part II the virtual loading regime and results. This work paves the way for the future estimation of mechanical properties in fossil mammalian bone.

Original languageEnglish
Article number20140186
Number of pages6
JournalJournal of the Royal Society Interface
Volume11
Issue number95
DOIs
Publication statusPublished - 6 Jun 2014

Keywords

  • finite-element analysis
  • vertebra
  • bone
  • mechanics
  • porcine
  • human
  • comparative
  • APOPHYSEAL JOINTS
  • LUMBAR VERTEBRAE
  • BONE
  • EVOLUTION
  • VALIDATION
  • MORPHOLOGY
  • DENSITY
  • STRESS

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