Comparing hospital and telephone follow-up for patients treated for stage-I endometrial cancer (ENDCAT trial): A randomised, multicentre, non-inferiority trial

Karen M Beaver*, S. Williamson, C Sutton, W. Hollingworth, A Gardner, B. Allton, M. Abdel-Aty, K. Blackwood, S. Burns, D. Curwen, R. Ghani, P. Keating, Stephen S. Murray, A. Tomlinson, B Walker, M. Willett, Neil Wood, P. Martin-Hirsch

*Corresponding author for this work

Research output: Contribution to journalArticle (Academic Journal)peer-review

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Abstract

Objective: To evaluate the effectiveness of nurse-led telephone follow-up (TFU) for patients with stage-I endometrial cancer. 

Design: Multicentre, randomised, non-inferiority trial. 

Setting: Five centres in the North West of England. 

Sample: A cohort of 259 women treated for stage-I endometrial cancer attending hospital outpatient clinics for routine follow-up. 

Methods: Participants were randomly allocated to receive traditional hospital based follow-up (HFU) or nurse-led TFU. 

Main outcome measures: Primary outcomes were psychological morbidity (State Trait Anxiety Inventory, STAI-S) and patient satisfaction with the information provided. Secondary outcomes included patient satisfaction with service, quality of life, and time to detection of recurrence. 

Results: The STAI-S scores post-randomisation were similar between groups [mean (SD): TFU 33.0 (11.0); HFU 35.5 (13.0)]. The estimated between-group difference in STAI-S was 0.7 (95% confidence interval, 95% CI -1.9 to 3.3); the confidence interval lies above the non-inferiority limit (-3.5), indicating the non-inferiority of TFU. There was no significant difference between groups in reported satisfaction with information (odds ratio, OR 0.9; 95% CI 0.4-2.1; P = 0.83). Women in the HFU group were more likely to report being kept waiting for their appointment (P = 0.001), that they did not need any information (P = 0.003), and were less likely to report that the nurse knew about their particular case and situation (P = 0.005). 

Conclusions: The TFU provides an effective alternative to HFU for patients with stage-I endometrial cancer, with no reported physical or psychological detriment. Patient satisfaction with information was high, with similar levels between groups. 

Tweetable abstract: ENDCAT trial shows effectiveness of nurse-led telephone follow-up for patients with stage-I endometrial cancer.

Original languageEnglish
Pages (from-to)150-160
Number of pages11
JournalBJOG: An International Journal of Obstetrics and Gynaecology
Volume124
Issue number1
Early online date7 Apr 2016
DOIs
Publication statusPublished - Jan 2017

Keywords

  • Endometrial cancer
  • Gynaecology
  • Morbidity
  • Oncology
  • Patient satisfaction
  • Psychological
  • Telephone follow-up

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