Comparing hospital and telephone follow-up for patients treated for stage-I endometrial cancer (ENDCAT trial): A randomised, multicentre, non-inferiority trial

Karen M Beaver; S. Williamson; C Sutton; W. Hollingworth; A Gardner; B. Allton; M. Abdel-Aty; K. Blackwood; S. Burns; D. Curwen; R. Ghani; P. Keating; Stephen S. Murray; A. Tomlinson; B Walker; M. Willett; Neil Wood; P. Martin-Hirsch

doi:10.1111/1471-0528.14000

Comparing hospital and telephone follow-up for patients treated for stage-I endometrial cancer (ENDCAT trial): A randomised, multicentre, non-inferiority trial

Karen M Beaver^*
, S. Williamson
, C Sutton
, W. Hollingworth
, A Gardner
, B. Allton
, M. Abdel-Aty
, K. Blackwood
, S. Burns
, D. Curwen
, R. Ghani
, P. Keating
, Stephen S. Murray
, A. Tomlinson
, B Walker
, M. Willett
, Neil Wood
, P. Martin-Hirsch

^*Corresponding author for this work

Research output: Contribution to journal › Article (Academic Journal) › peer-review

90 Citations (Scopus)

1034 Downloads (Pure)

Abstract

Objective: To evaluate the effectiveness of nurse-led telephone follow-up (TFU) for patients with stage-I endometrial cancer.

Design: Multicentre, randomised, non-inferiority trial.

Setting: Five centres in the North West of England.

Sample: A cohort of 259 women treated for stage-I endometrial cancer attending hospital outpatient clinics for routine follow-up.

Methods: Participants were randomly allocated to receive traditional hospital based follow-up (HFU) or nurse-led TFU.

Main outcome measures: Primary outcomes were psychological morbidity (State Trait Anxiety Inventory, STAI-S) and patient satisfaction with the information provided. Secondary outcomes included patient satisfaction with service, quality of life, and time to detection of recurrence.

Results: The STAI-S scores post-randomisation were similar between groups [mean (SD): TFU 33.0 (11.0); HFU 35.5 (13.0)]. The estimated between-group difference in STAI-S was 0.7 (95% confidence interval, 95% CI -1.9 to 3.3); the confidence interval lies above the non-inferiority limit (-3.5), indicating the non-inferiority of TFU. There was no significant difference between groups in reported satisfaction with information (odds ratio, OR 0.9; 95% CI 0.4-2.1; P = 0.83). Women in the HFU group were more likely to report being kept waiting for their appointment (P = 0.001), that they did not need any information (P = 0.003), and were less likely to report that the nurse knew about their particular case and situation (P = 0.005).

Conclusions: The TFU provides an effective alternative to HFU for patients with stage-I endometrial cancer, with no reported physical or psychological detriment. Patient satisfaction with information was high, with similar levels between groups.

Tweetable abstract: ENDCAT trial shows effectiveness of nurse-led telephone follow-up for patients with stage-I endometrial cancer.

Original language	English
Pages (from-to)	150-160
Number of pages	11
Journal	BJOG: An International Journal of Obstetrics and Gynaecology
Volume	124
Issue number	1
Early online date	7 Apr 2016
DOIs	https://doi.org/10.1111/1471-0528.14000
Publication status	Published - Jan 2017

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Endometrial cancer
Gynaecology
Morbidity
Oncology
Patient satisfaction
Psychological
Telephone follow-up

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Accepted author manuscript, 382 KB
ENDCAT CONSORT Flow Diagram Figure 1 V2Other version, 269 KB
Table 1 ENDCATOther version, 103 KB
Table 2 ENDCATOther version, 193 KB
Table 3 ENDCAT

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Beaver, K. M., Williamson, S., Sutton, C., Hollingworth, W., Gardner, A., Allton, B., Abdel-Aty, M., Blackwood, K., Burns, S., Curwen, D., Ghani, R., Keating, P., Murray, S. S., Tomlinson, A., Walker, B., Willett, M., Wood, N., & Martin-Hirsch, P. (2017). Comparing hospital and telephone follow-up for patients treated for stage-I endometrial cancer (ENDCAT trial): A randomised, multicentre, non-inferiority trial. BJOG: An International Journal of Obstetrics and Gynaecology, 124(1), 150-160. https://doi.org/10.1111/1471-0528.14000

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title = "Comparing hospital and telephone follow-up for patients treated for stage-I endometrial cancer (ENDCAT trial): A randomised, multicentre, non-inferiority trial",

abstract = "Objective: To evaluate the effectiveness of nurse-led telephone follow-up (TFU) for patients with stage-I endometrial cancer. Design: Multicentre, randomised, non-inferiority trial. Setting: Five centres in the North West of England. Sample: A cohort of 259 women treated for stage-I endometrial cancer attending hospital outpatient clinics for routine follow-up. Methods: Participants were randomly allocated to receive traditional hospital based follow-up (HFU) or nurse-led TFU. Main outcome measures: Primary outcomes were psychological morbidity (State Trait Anxiety Inventory, STAI-S) and patient satisfaction with the information provided. Secondary outcomes included patient satisfaction with service, quality of life, and time to detection of recurrence. Results: The STAI-S scores post-randomisation were similar between groups [mean (SD): TFU 33.0 (11.0); HFU 35.5 (13.0)]. The estimated between-group difference in STAI-S was 0.7 (95\% confidence interval, 95\% CI -1.9 to 3.3); the confidence interval lies above the non-inferiority limit (-3.5), indicating the non-inferiority of TFU. There was no significant difference between groups in reported satisfaction with information (odds ratio, OR 0.9; 95\% CI 0.4-2.1; P = 0.83). Women in the HFU group were more likely to report being kept waiting for their appointment (P = 0.001), that they did not need any information (P = 0.003), and were less likely to report that the nurse knew about their particular case and situation (P = 0.005). Conclusions: The TFU provides an effective alternative to HFU for patients with stage-I endometrial cancer, with no reported physical or psychological detriment. Patient satisfaction with information was high, with similar levels between groups. Tweetable abstract: ENDCAT trial shows effectiveness of nurse-led telephone follow-up for patients with stage-I endometrial cancer.",

keywords = "Endometrial cancer, Gynaecology, Morbidity, Oncology, Patient satisfaction, Psychological, Telephone follow-up",

author = "Beaver, \{Karen M\} and S. Williamson and C Sutton and W. Hollingworth and A Gardner and B. Allton and M. Abdel-Aty and K. Blackwood and S. Burns and D. Curwen and R. Ghani and P. Keating and Murray, \{Stephen S.\} and A. Tomlinson and B Walker and M. Willett and Neil Wood and P. Martin-Hirsch",

year = "2017",

month = jan,

doi = "10.1111/1471-0528.14000",

language = "English",

volume = "124",

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Beaver, KM, Williamson, S, Sutton, C, Hollingworth, W, Gardner, A, Allton, B, Abdel-Aty, M, Blackwood, K, Burns, S, Curwen, D, Ghani, R, Keating, P, Murray, SS, Tomlinson, A, Walker, B, Willett, M, Wood, N & Martin-Hirsch, P 2017, 'Comparing hospital and telephone follow-up for patients treated for stage-I endometrial cancer (ENDCAT trial): A randomised, multicentre, non-inferiority trial', BJOG: An International Journal of Obstetrics and Gynaecology, vol. 124, no. 1, pp. 150-160. https://doi.org/10.1111/1471-0528.14000

Comparing hospital and telephone follow-up for patients treated for stage-I endometrial cancer (ENDCAT trial): A randomised, multicentre, non-inferiority trial. / Beaver, Karen M; Williamson, S.; Sutton, C et al.
In: BJOG: An International Journal of Obstetrics and Gynaecology, Vol. 124, No. 1, 01.2017, p. 150-160.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

TY - JOUR

T1 - Comparing hospital and telephone follow-up for patients treated for stage-I endometrial cancer (ENDCAT trial)

T2 - A randomised, multicentre, non-inferiority trial

AU - Beaver, Karen M

AU - Williamson, S.

AU - Sutton, C

AU - Hollingworth, W.

AU - Gardner, A

AU - Allton, B.

AU - Abdel-Aty, M.

AU - Blackwood, K.

AU - Burns, S.

AU - Curwen, D.

AU - Ghani, R.

AU - Keating, P.

AU - Murray, Stephen S.

AU - Tomlinson, A.

AU - Walker, B

AU - Willett, M.

AU - Wood, Neil

AU - Martin-Hirsch, P.

PY - 2017/1

Y1 - 2017/1

N2 - Objective: To evaluate the effectiveness of nurse-led telephone follow-up (TFU) for patients with stage-I endometrial cancer. Design: Multicentre, randomised, non-inferiority trial. Setting: Five centres in the North West of England. Sample: A cohort of 259 women treated for stage-I endometrial cancer attending hospital outpatient clinics for routine follow-up. Methods: Participants were randomly allocated to receive traditional hospital based follow-up (HFU) or nurse-led TFU. Main outcome measures: Primary outcomes were psychological morbidity (State Trait Anxiety Inventory, STAI-S) and patient satisfaction with the information provided. Secondary outcomes included patient satisfaction with service, quality of life, and time to detection of recurrence. Results: The STAI-S scores post-randomisation were similar between groups [mean (SD): TFU 33.0 (11.0); HFU 35.5 (13.0)]. The estimated between-group difference in STAI-S was 0.7 (95% confidence interval, 95% CI -1.9 to 3.3); the confidence interval lies above the non-inferiority limit (-3.5), indicating the non-inferiority of TFU. There was no significant difference between groups in reported satisfaction with information (odds ratio, OR 0.9; 95% CI 0.4-2.1; P = 0.83). Women in the HFU group were more likely to report being kept waiting for their appointment (P = 0.001), that they did not need any information (P = 0.003), and were less likely to report that the nurse knew about their particular case and situation (P = 0.005). Conclusions: The TFU provides an effective alternative to HFU for patients with stage-I endometrial cancer, with no reported physical or psychological detriment. Patient satisfaction with information was high, with similar levels between groups. Tweetable abstract: ENDCAT trial shows effectiveness of nurse-led telephone follow-up for patients with stage-I endometrial cancer.

AB - Objective: To evaluate the effectiveness of nurse-led telephone follow-up (TFU) for patients with stage-I endometrial cancer. Design: Multicentre, randomised, non-inferiority trial. Setting: Five centres in the North West of England. Sample: A cohort of 259 women treated for stage-I endometrial cancer attending hospital outpatient clinics for routine follow-up. Methods: Participants were randomly allocated to receive traditional hospital based follow-up (HFU) or nurse-led TFU. Main outcome measures: Primary outcomes were psychological morbidity (State Trait Anxiety Inventory, STAI-S) and patient satisfaction with the information provided. Secondary outcomes included patient satisfaction with service, quality of life, and time to detection of recurrence. Results: The STAI-S scores post-randomisation were similar between groups [mean (SD): TFU 33.0 (11.0); HFU 35.5 (13.0)]. The estimated between-group difference in STAI-S was 0.7 (95% confidence interval, 95% CI -1.9 to 3.3); the confidence interval lies above the non-inferiority limit (-3.5), indicating the non-inferiority of TFU. There was no significant difference between groups in reported satisfaction with information (odds ratio, OR 0.9; 95% CI 0.4-2.1; P = 0.83). Women in the HFU group were more likely to report being kept waiting for their appointment (P = 0.001), that they did not need any information (P = 0.003), and were less likely to report that the nurse knew about their particular case and situation (P = 0.005). Conclusions: The TFU provides an effective alternative to HFU for patients with stage-I endometrial cancer, with no reported physical or psychological detriment. Patient satisfaction with information was high, with similar levels between groups. Tweetable abstract: ENDCAT trial shows effectiveness of nurse-led telephone follow-up for patients with stage-I endometrial cancer.

KW - Endometrial cancer

KW - Gynaecology

KW - Morbidity

KW - Oncology

KW - Patient satisfaction

KW - Psychological

KW - Telephone follow-up

UR - https://www.scopus.com/pages/publications/84963787999

U2 - 10.1111/1471-0528.14000

DO - 10.1111/1471-0528.14000

M3 - Article (Academic Journal)

C2 - 27062690

AN - SCOPUS:84963787999

SN - 1470-0328

VL - 124

SP - 150

EP - 160

JO - BJOG: An International Journal of Obstetrics and Gynaecology

JF - BJOG: An International Journal of Obstetrics and Gynaecology

IS - 1

ER -

Beaver KM, Williamson S, Sutton C, Hollingworth W, Gardner A, Allton B et al. Comparing hospital and telephone follow-up for patients treated for stage-I endometrial cancer (ENDCAT trial): A randomised, multicentre, non-inferiority trial. BJOG: An International Journal of Obstetrics and Gynaecology. 2017 Jan;124(1):150-160. Epub 2016 Apr 7. doi: 10.1111/1471-0528.14000

Comparing hospital and telephone follow-up for patients treated for stage-I endometrial cancer (ENDCAT trial): A randomised, multicentre, non-inferiority trial

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Comparing hospital and telephone follow-up for patients treated for stage-I endometrial cancer (ENDCAT trial): A randomised, multicentre, non-inferiority trial

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UN SDGs

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Access to Document

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