Projects per year
Methods: Hair samples were collected from 136 subjects who were self-reported heavy, light or non-users of cannabis and tested using GC-MS/MS. Sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) were calculated for 5 cannabinoids (THC, THC-OH, THC-COOH, Cannabinol and Cannabidiol). Samples also were segmented in 1 cm sections representing 1 month exposure and the correlation between amount of cannabinoid detected and self-reported cannabis consumption tested.
Results: All 5 cannabinoids were detected. 77% of heavy users, 39% of light users and 0% of non-users tested positive for THC. The sensitivity of detection of THC was 0.77 (0.56-0.91) comparing heavy cannabis smokers with light and non-users, whereas the sensitivity of other cannabinoids generally was considerably lower. The PPV and NPV of detection of THC were 0.57 (0.39-0.74) and 0.91 (0.82-0.97), respectively. A correlation of 0.52 (p<0.001) was observed between self-reported monthly cannabis use and THC.
Discussion: Hair analysis can be used as a qualitative indicator of heavy (daily or near daily) cannabis consumption within the past 3 months. However, this approach is unable to reliably detect light cannabis consumption or determine the quantity of cannabis used by the individual.
- Hair testing
1/06/15 → 31/05/20
1/05/09 → 1/04/13