Composite outcomes: weighting component events according to severity assisted interpretation but reduced statistical power

Uchechukwu K A Sampson, Chris Metcalfe, Marc A Pfeffer, Scott D Solomon, Kelly H Zou

Research output: Contribution to journalArticle (Academic Journal)peer-review

12 Citations (Scopus)

Abstract

In trials of chronic disease therapy, each patient may experience several nonfatal illnesses and death. "Composite" outcome measures combine information from these different components of disease burden. Most common is the binary distinction between patients undergoing one or more events and those undergoing no events. We compare this approach with a composite score that preserves information on the number and severity of events.
Original languageEnglish
Pages (from-to)1156-8
Number of pages3
JournalJournal of Clinical Epidemiology
Volume63
Issue number10
DOIs
Publication statusPublished - 2010

Fingerprint Dive into the research topics of 'Composite outcomes: weighting component events according to severity assisted interpretation but reduced statistical power'. Together they form a unique fingerprint.

Cite this