Composite scaffolds for large bone defects

Evangelos Daskalakis, Fengyuan Liu, Glen Cooper, Andy Weightman, Bahattin Koc, Gordon Blunn, Paulo Bartolo*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference Contribution (Conference Proceeding)

2 Citations (Scopus)


This paper investigates the use of polymer-ceramic composite scaffolds for bone regeneration. Different ratios between Poly-εcaprolactone (PCL) and Hydroxyapatite (HA) were considered. Scaffolds were produced using two different lay-down patterns (0/90° and 0/45°), and pore sizes (350 μm, 500 μm and 700 μm). Compressive and cell proliferation tests are reported. Human adipose derived stem cells (hADSCs) were used for the biological characterization.
Original languageEnglish
Title of host publicationProgress in Digital and Physical Manufacturing
Subtitle of host publicationProceedings of ProDPM'19
ISBN (Electronic)978-3-030-29041-2
ISBN (Print)978-3-030-29040-5, 978-3-030-29043-6
Publication statusPublished - 2020

Publication series

NameLecture Notes in Mechanical Engineering
PublisherSpringer International Publishing
ISSN (Print)2195-4356


  • Hydroxyapatite
  • Bioprinting
  • Additive manufacturing
  • Tissue engineering


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