Concise Entries to 4-Halo- and 3-Bromo-4-halo-2-pyridones

Timothy Gallagher; Aurelien Honraedt

doi:10.1055/s-0035-1560469

Concise Entries to 4-Halo- and 3-Bromo-4-halo-2-pyridones

Timothy Gallagher, Aurelien Honraedt

Research output: Contribution to journal › Letter (Academic Journal) › peer-review

4 Citations (Scopus)

370 Downloads (Pure)

Abstract

Methods for the synthesis of both simple 4-halo-2-pyridones and more functionalized 3,4-di-and (3,4,5-tri) halo-2-pyridones are described that are based on a combination of Sandmeyer and regioselective (Cu-mediated) halogenation, with a 2-chloro or a 2-benzyloxy moiety serving as a masked 2-pyridone.

Original language	English
Pages (from-to)	67-69
Number of pages	3
Journal	SYNLETT
Volume	27
Issue number	1
Early online date	8 Sept 2015
DOIs	https://doi.org/10.1055/s-0035-1560469
Publication status	Published - Jan 2016

Keywords

polyhalopyridone
pyridines
Sandmeyer reaction
halogenation

Access to Document

10.1055/s-0035-1560469

Halopyridones_Synlett_template_FINALAccepted author manuscript, 64.3 KB

Handle.net

Persistent link

3-month Core Capability for Chemistry Research
Crosby, J.
1/01/13 → 1/04/13
Project: Research

Cite this

@article{ce682f600411478083ff26c2bc448a87,

title = "Concise Entries to 4-Halo- and 3-Bromo-4-halo-2-pyridones",

abstract = "Methods for the synthesis of both simple 4-halo-2-pyridones and more functionalized 3,4-di-and (3,4,5-tri) halo-2-pyridones are described that are based on a combination of Sandmeyer and regioselective (Cu-mediated) halogenation, with a 2-chloro or a 2-benzyloxy moiety serving as a masked 2-pyridone.",

keywords = "polyhalopyridone, pyridines, Sandmeyer reaction, halogenation",

author = "Timothy Gallagher and Aurelien Honraedt",

year = "2016",

month = jan,

doi = "10.1055/s-0035-1560469",

language = "English",

volume = "27",

pages = "67--69",

journal = "SYNLETT",

issn = "0936-5214",

publisher = "Georg Thieme Verlag",

number = "1",

}

TY - JOUR

T1 - Concise Entries to 4-Halo- and 3-Bromo-4-halo-2-pyridones

AU - Gallagher, Timothy

AU - Honraedt, Aurelien

PY - 2016/1

Y1 - 2016/1

N2 - Methods for the synthesis of both simple 4-halo-2-pyridones and more functionalized 3,4-di-and (3,4,5-tri) halo-2-pyridones are described that are based on a combination of Sandmeyer and regioselective (Cu-mediated) halogenation, with a 2-chloro or a 2-benzyloxy moiety serving as a masked 2-pyridone.

AB - Methods for the synthesis of both simple 4-halo-2-pyridones and more functionalized 3,4-di-and (3,4,5-tri) halo-2-pyridones are described that are based on a combination of Sandmeyer and regioselective (Cu-mediated) halogenation, with a 2-chloro or a 2-benzyloxy moiety serving as a masked 2-pyridone.

KW - polyhalopyridone

KW - pyridines

KW - Sandmeyer reaction

KW - halogenation

U2 - 10.1055/s-0035-1560469

DO - 10.1055/s-0035-1560469

M3 - Letter (Academic Journal)

SN - 0936-5214

VL - 27

SP - 67

EP - 69

JO - SYNLETT

JF - SYNLETT

IS - 1

ER -

Concise Entries to 4-Halo- and 3-Bromo-4-halo-2-pyridones

Abstract

Keywords

Access to Document

Handle.net

Fingerprint

Projects

3-month Core Capability for Chemistry Research

Cite this