Conformationally Constrained Glycosyl Donors as Tools to Control Glycosylation Outcomes

Robin A Jeanneret, Simon E Johnson, M Carmen Galan*

*Corresponding author for this work

Research output: Contribution to journalArticle (Academic Journal)

Abstract

The stereoselective synthesis of oligosaccharides remains one of the biggest challenges in carbohydrate chemistry. Many factors, including reaction conditions and the type of glycosyl donor and acceptor used, can affect the outcome of glycosylation reactions. In this Perspective, we discuss methods aimed to control the reactivity and stereoselectivity of glycosylation reactions using conformationally constrained glycosyl donors, with a focus on more recently developed chemistry.

Original languageEnglish
Number of pages26
JournalJournal of Organic Chemistry
Volume(2020)
Early online date26 Oct 2020
DOIs
Publication statusE-pub ahead of print - 26 Oct 2020

Structured keywords

  • BCS and TECS CDTs

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