TY - JOUR
T1 - Consensus Paper
T2 - Current Views on the Role of Cerebellar Interpositus Nucleus in Movement Control and Emotion
AU - Perciavalle, Vincenzo
AU - Apps, Richard
AU - Bracha, Vlastislav
AU - Delgado-García, José M
AU - Gibson, Alan R
AU - Leggio, Maria
AU - Carrel, Andrew J
AU - Cerminara, Nadia
AU - Coco, Marinella
AU - Gruart, Agnès
AU - Sánchez-Campusano, Raudel
PY - 2013/4/7
Y1 - 2013/4/7
N2 - In the present paper, we examine the role of the cerebellar interpositus nucleus (IN) in motor and non-motor domains. Recent findings are considered, and we share the following conclusions: IN as part of the olivo-cortico-nuclear microcircuit is involved in providing powerful timing signals important in coordinating limb movements; IN could participate in the timing and performance of ongoing conditioned responses rather than the generation and/or initiation of such responses; IN is involved in the control of reflexive and voluntary movements in a task- and effector system-dependent fashion, including hand movements and associated upper limb adjustments, for quick effective actions; IN develops internal models for dynamic interactions of the motor system with the external environment for anticipatory control of movement; and IN plays a significant role in the modulation of autonomic and emotional functions.
AB - In the present paper, we examine the role of the cerebellar interpositus nucleus (IN) in motor and non-motor domains. Recent findings are considered, and we share the following conclusions: IN as part of the olivo-cortico-nuclear microcircuit is involved in providing powerful timing signals important in coordinating limb movements; IN could participate in the timing and performance of ongoing conditioned responses rather than the generation and/or initiation of such responses; IN is involved in the control of reflexive and voluntary movements in a task- and effector system-dependent fashion, including hand movements and associated upper limb adjustments, for quick effective actions; IN develops internal models for dynamic interactions of the motor system with the external environment for anticipatory control of movement; and IN plays a significant role in the modulation of autonomic and emotional functions.
U2 - 10.1007/s12311-013-0464-0
DO - 10.1007/s12311-013-0464-0
M3 - Article (Academic Journal)
C2 - 23564049
SN - 1473-4222
VL - 12
SP - 738
EP - 757
JO - Cerebellum
JF - Cerebellum
IS - 5
ER -