This articlereports three experiments that investigate the role ofcontext in repetition priming using a lexical decision task. The experiments show that repetition priming is either eliminated or significantly reduced if a change in context also alters the perceived sense of a nonhomographic target word. If perceived sense is not altered, a change in context is inconsequential. This points to the important role played by perceived sense in repetition priming. An explanation within a sense-specific activation framework is proposed in preference to a modified processing view.