Cord blood leptin is associated with size at birth and predicts infancy weight gain in humans

KKL Ong, ML Ahmed, AM Sherriff, KA Woods, A Watts, J Golding, Team the ALSPAC Study, DB Dunger

Research output: Contribution to journalArticle (Academic Journal)peer-review

205 Citations (Scopus)

Abstract

Recent discoveries of human genetic leptin deficiency have demonstrated its importance in regulating weight gain in early childhood. To investigate whether normal variation in leptin and insulin levels in cord blood could influence infancy growth, we assayed samples from 197 infants from a representative birth cohort, who were measured at birth, 4, 8, 12 and 24 months. Cord leptin levels correlated most closely with weight and ponderal index (kg/m3) at birth, but also with length and head circumference (all P
Translated title of the contributionCord blood leptin is associated with size at birth and predicts infancy weight gain in humans
Original languageEnglish
Pages (from-to)1145 - 1148
Number of pages4
JournalJournal of Clinical Endocrinology and Metabolism
Volume84 (3)
Publication statusPublished - Mar 1999

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