Abstract
Recent discoveries of human genetic leptin deficiency have demonstrated its importance in regulating weight gain in early childhood. To investigate whether normal variation in leptin and insulin levels in cord blood could influence infancy growth, we assayed samples from 197 infants from a representative birth cohort, who were measured at birth, 4, 8, 12 and 24 months. Cord leptin levels correlated most closely with weight and ponderal index (kg/m3) at birth, but also with length and head circumference (all P
Translated title of the contribution | Cord blood leptin is associated with size at birth and predicts infancy weight gain in humans |
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Original language | English |
Pages (from-to) | 1145 - 1148 |
Number of pages | 4 |
Journal | Journal of Clinical Endocrinology and Metabolism |
Volume | 84 (3) |
Publication status | Published - Mar 1999 |