Projects per year
Abstract
BACKGROUND: Depression is expensive to treat, but providing ineffective treatment is more expensive. Such is the case for many patients who do not respond to antidepressant medication.
AIMS: To assess the cost-effectiveness of cognitive-behavioural therapy (CBT) plus usual care for primary care patients with treatment-resistant depression compared with usual care alone.
METHOD: Economic evaluation at 12 months alongside a randomised controlled trial. Cost-effectiveness assessed using a cost-consequences framework comparing cost to the health and social care provider, patients and society, with a range of outcomes. Cost-utility analysis comparing health and social care costs with quality-adjusted life-years (QALYs).
RESULTS: The mean cost of CBT per participant was £910. The difference in QALY gain between the groups was 0.057, equivalent to 21 days a year of good health. The incremental cost-effectiveness ratio was £14 911 (representing a 74% probability of the intervention being cost-effective at the National Institute of Health and Care Excellence threshold of £20 000 per QALY). Loss of earnings and productivity costs were substantial but there was no evidence of a difference between intervention and control groups.
CONCLUSIONS: The addition of CBT to usual care is cost-effective in patients who have not responded to antidepressants. Primary care physicians should therefore be encouraged to refer such individuals for CBT.
Original language | English |
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Pages (from-to) | 69-76 |
Number of pages | 8 |
Journal | British Journal of Psychiatry |
Volume | 204 |
Issue number | 1 |
Early online date | 21 Nov 2013 |
DOIs | |
Publication status | Published - Jan 2014 |
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Dive into the research topics of 'Cost-effectiveness of cognitive-behavioural therapy as an adjunct to pharmacotherapy for treatment-resistant depression in primary care: economic evaluation of the CoBalT Trial'. Together they form a unique fingerprint.Projects
- 1 Finished
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COLLABORATION AND INNOVATION IN DIFFICULT OR RANDOMISED CONTROLLED TRIALS
Blazeby, J. (Principal Investigator)
1/04/09 → 1/04/14
Project: Research
Profiles
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Professor David S Kessler
- Bristol Medical School (PHS) - Professor of Primary Care
- Bristol Population Health Science Institute
- Centre for Academic Mental Health
- Centre for Academic Primary Care
Person: Academic , Member
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Professor Tim Peters
- Bristol Dental School - Professor
- Bristol Population Health Science Institute
- Centre for Academic Primary Care
Person: Academic , Member
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Professor Katrina M Turner
- Bristol Medical School (PHS) - Professor of Primary Care Research
- Bristol Population Health Science Institute
- Centre for Academic Mental Health
- Cancer
- Centre for Academic Primary Care
Person: Academic , Member